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D5764

Sigma-Aldrich

2,3-Diphospho-D-glyceric acid pentasodium salt

glycolysis metabolite

Synonym(e):

2,3-DPG, D-Glycerate 2,3-diphosphate sodium salt

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About This Item

Lineare Formel:
C3H3O10P2Na5
CAS-Nummer:
102783-53-9
Molekulargewicht:
375.95
MDL-Nummer:
MFCD00070074
UNSPSC-Code:
12352201
PubChem Substanz-ID:
24893967
NACRES:
NA.25

Biologische Quelle

synthetic

Qualitätsniveau

200

Form

powder

Verunreinigungen

3-phosphoglyceric acid, essentially free

Farbe

white to off-white

Löslichkeit

water: 100 mg/mL, clear, colorless to faintly yellow

Kationenspuren

Na: 24.5-32.5% (anhydrous)

Lagertemp.

−20°C

SMILES String

[Na].OC(=O)[C@@H](COP(O)(O)=O)OP(O)(O)=O

InChI

1S/C3H8O10P2.Na.H/c4-3(5)2(13-15(9,10)11)1-12-14(6,7)8;;/h2H,1H2,(H,4,5)(H2,6,7,8)(H2,9,10,11);;/t2-;;/m1../s1

InChIKey

JJEMSNINYKJOBZ-YBBRRFGFSA-N

Anwendung

D-Glycerate 2,3-diphosphate, cofactor of both phosphoglyceric acid mutase and hemoglobin, may be used as a reference compound in analysis of blood cell (erythrocyte) glycolysic cycle metabolites.

Biochem./physiol. Wirkung

Metabolite of glycolysis within human erythrocytes produced by 2,3-diphosphoglycerate mutase in an alternative to the glycolytic pathway. Binds to hemaglobin to reduce oxygenation.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

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Manon Bardyn et al.
Metabolites, 10(6) (2020-06-04)
After blood donation, the red blood cells (RBCs) for transfusion are generally isolated by centrifugation and then filtrated and supplemented with additive solution. The consecutive changes of the extracellular environment participate to the occurrence of storage lesions. In this study
H Gulliksson et al.
Vox sanguinis, 112(1), 33-39 (2016-12-22)
The present general plasticizer di-2-ethylhexyl-phthalate in polyvinylchloride (PVC) blood bags is only physically dispersed in PVC and will therefore leach into blood components. The objective of this study was to perform a first preliminary red blood cell (RBC) storage evaluation
Sitong Zhou et al.
Science advances, 5(5), eaaw4466-eaaw4466 (2019-06-01)
The tight coupling between cerebral blood flow and neural activity is a key feature of normal brain function and forms the basis of functional hyperemia. The mechanisms coupling neural activity to vascular responses, however, remain elusive despite decades of research.
Aabhas Mathur et al.
Transfusion, 56(12), 2941-2947 (2016-10-06)
Each unit of blood donated is processed and stored individually resulting in variability in the amount of red blood cells (RBCs) collected, RBC properties, and the 24-hour posttransfusion RBC survivability. As a result, each unit differs in its ability to
Vivek P Jani et al.
IEEE transactions on biomedical circuits and systems, 11(6), 1400-1405 (2017-10-06)
In 2013, nearly 15 million units of banked blood were transfused in the United States of America alone. Blood shortages are expected to increase globally. Donated blood is not equal due to differences in quality and deterioration rate. There are
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