C6767

Kongorot

Dye content ≥35 %, Powder

• Synonym(e): Direktrot 28, Kongorot 4B
• Empirische Formel (Hill-System): C₃₂H₂₂N₆Na₂O₆S₂
• CAS-Nummer: 573-58-0
• Molekulargewicht: 696.66
• Farbindexnummer: 22120
• Beilstein: 3894858
• EG-Nummer: 209-358-4
• MDL-Nummer: MFCD00004028
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24892892
• NACRES: NA.47

Eigenschaften

• product name: Kongorot, Dye content ≥35 %
• Form: powder
• Qualitätsniveau: 200
• Zusammensetzung: Dye content, ≥35%
• Methode(n): titration: suitable
• Farbe: red-brown
• pH-Wert: 6.7 (10 g/L)
• mp (Schmelzpunkt): >360 °C (lit.)
• Löslichkeit: H₂O: 1 mg/mL
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: [Na+].[Na+].Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c3ccc(cc3)-c4ccc(cc4)\N=N\c5cc(c6ccccc6c5N)S([O-])(=O)=O
• InChI: 1S/C32H24N6O6S2.2Na/c33-31-25-7-3-1-5-23(25)29(45(39,40)41)17-27(31)37-35-21-13-9-19(10-14-21)20-11-15-22(16-12-20)36-38-28-18-30(46(42,43)44)24-6-2-4-8-26(24)32(28)34;;/h1-18H,33-34H2,(H,39,40,41)(H,42,43,44);;/q;2*+1/p-2/b37-35+,38-36+;;
• InChIKey: IQFVPQOLBLOTPF-HKXUKFGYSA-L

Beschreibung

Anwendung

• Congo red has been used as a histochemical stain for the quantification of amyloid deposits in brain tissues.
• It has been used as a cell wall inhibiting agent in fungus Cryptococcus neoformans.
• It has also been used to study microstructural details in the cell walls of raw potato and fried potato using confocal microscopy.

Biochem./physiol. Wirkung

Congo red is a benzidine-based anionic diazo dye. It is a histological dye which binds to many amyloid proteins and is used for the quantification of amyloid β-peptide aggregation. Congo red also interacts with β-D-glucans, polysaccharides containing continuous β-(1→4)-linked D-glucopyranosyl units and some hemicellulosic galactoglucomannans.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H350,H361d
• P-Sätze: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Gefahreneinstufungen: Carc. 1B - Repr. 2
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type P3 (EN 143) respirator cartridges