C3167
Corticotropin Releasing Factor sheep
≥95% (HPLC)
Synonym(e):
CRF, CRH
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About This Item
Empirische Formel (Hill-System):
C205H339N59O63S
CAS-Nummer:
Molekulargewicht:
4670.31
MDL-Nummer:
UNSPSC-Code:
12352200
NACRES:
NA.32
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Amino Acid Sequence
Ser-Gln-Glu-Pro-Pro-Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Thr-Lys-Ala-Asp-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser-Asn-Arg-Lys-Leu-Leu-Asp-Ile-Ala-NH2
Biochem./physiol. Wirkung
CRF is a hypothalamic peptide that releases ACTH and endorphin from the anterior pituitary. It is also a neurotransmitter in the central nervous system, and is involved in autonomic and endocrine responses to stress.
Sonstige Hinweise
Lyophilized from 0.1% TFA in H2O
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
Analysenzertifikate (COA)
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Susan K Wood et al.
American journal of physiology. Regulatory, integrative and comparative physiology, 304(11), R940-R950 (2013-04-05)
Barrington's nucleus, in the pons, regulates micturition through spinal projections to preganglionic parasympathetic neurons. The stress neuropeptide CRF is prominent in these projections and has an inhibitory influence. Social stress in rats causes urinary retention and abnormal urodynamics resembling those
Neuroscience. Plasticity in the neurotransmitter repertoire.
Susan J Birren et al.
Science (New York, N.Y.), 340(6131), 436-437 (2013-04-27)
Joshua J Wind et al.
The Journal of clinical endocrinology and metabolism, 98(6), 2285-2293 (2013-04-05)
It is often difficult to find an adenoma in patients with Cushing's disease (CD) whose preoperative magnetic resonance imaging (MRI) is normal. Better localizing modalities are needed. The aim of this study was to determine the accuracy of inferior petrosal
Cun Li et al.
Endocrinology, 154(7), 2365-2373 (2013-04-30)
Intrauterine growth restriction (IUGR) is an important fetal developmental problem resulting from 2 broad causes: maternal undernutrition and/or decreased fetal nutrient delivery to the fetus via placental insufficiency. IUGR is often accompanied by up-regulation of the hypothalamo-pituitary-adrenal axis (HPAA). Sheep
L O E Ebbesson et al.
Journal of neuroendocrinology, 23(8), 733-741 (2011-05-20)
Salmon parr-smolt transformation (smoltification) is a mid-life transitional stage between life in freshwater and seawater that entails a wide range of neural, endocrine and physiological modifications. In salmon, the neuroendocrine corticotropin-releasing factor (CRF) system regulates pituitary adrenocorticotrophic hormone and thyrotrophin
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