C2394

5-Cholesten-3β-ol-7-on

≥90%

• Synonym(e): 3β-Hydroxy-5-cholesten-7-one, 7-Ketocholesterol
• Empirische Formel (Hill-System): C₂₇H₄₄O₂
• CAS-Nummer: 566-28-9
• Molekulargewicht: 400.64
• MDL-Nummer: MFCD00010474
• UNSPSC-Code: 41141804
• PubChem Substanz-ID: 24892324
• NACRES: NA.77

Eigenschaften

• Biologische Quelle: synthetic (organic)
• Assay: ≥90%
• Form: powder
• Funktionelle Gruppe: ketone
• Versandbedingung: ambient
• Lagertemp.: room temp
• SMILES String: C[C@]12CC[C@@]([C@](CC[C@H](O)C3)(C)C3=CC4=O)([H])[C@]4([H])[C@]1([H])CC[C@]2([H])[C@]([H])(C)CCCC(C)C
• InChI: 1S/C27H44O2/c1-17(2)7-6-8-18(3)21-9-10-22-25-23(12-14-27(21,22)5)26(4)13-11-20(28)15-19(26)16-24(25)29/h16-18,20-23,25,28H,6-15H2,1-5H3/t18-,20+,21-,22+,23+,25+,26+,27-/m1/s1
• InChIKey: YIKKMWSQVKJCOP-ABXCMAEBSA-N

Beschreibung

Anwendung

5-Cholesten-3β-ol-7-one was used as a standard in the determination of cholesterol derivatives by GC-MS and HPLC.

Biochem./physiol. Wirkung

5-Cholesten-3β-ol-7-one is a cholesterol derivative that decreases the membrane potential of lipid bilayers. It reportedly accumulates in atherosclerotic plaques that leads to apoptosis of vascular cells.

Angaben zur Herstellung

5-Cholesten-3β-ol-7-one yields clear to slightly hazy, colorless to faint yellow solution in chloroform at 250 mg/5 ml.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)