C1608

Monoclonal Anti-Cellular Retinoic Acid Binding Protein 1 antibody produced in mouse

clone C-1, ascites fluid, buffered aqueous solution

• Synonym(e): Anti-CRABP 1
• MDL-Nummer: MFCD02262690
• UNSPSC-Code: 12352203
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 200
• Konjugat: unconjugated
• Antikörperform: ascites fluid
• Antikörper-Produkttyp: primary antibodies
• Klon: C-1, monoclonal
• Form: buffered aqueous solution
• Mol-Gew.: antigen 16 kDa
• Speziesreaktivität: feline, turtle, monkey, rabbit, bovine, human, rat, chicken
• Darf nicht reagieren mit: (chameleon), frog, goldfish
• Methode(n): indirect ELISA: suitable; western blot: suitable
• UniProt-Hinterlegungsnummer: P29762
• Versandbedingung: wet ice
• Lagertemp.: −20°C
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CRABP1(1381) ; rat ... Crabp1(25061)

Beschreibung

Allgemeine Beschreibung

Cellular retinoic acid-binding protein 1 is a protein encoded by the CRABP1 gene in humans. It encodes a specific binding protein for a vitamin A family member. It is also referred as RBP5, CRABP, CRABPI and CRABP-I.

Immunogen

performic acid oxidized CRABP 1, purified from bovine retina.

Anwendung

Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Western Blotting (1 paper)

Monoclonal Anti-Cellular Retinoic Acid Binding Protein 1 antibody produced in mouse is suitable for the following applications:

• indirect ELISA
• western blotting at a dilution of 1:1000
• immunofluorescence at a working dilution of 1:250

Biochem./physiol. Wirkung

Cellular retinoic acid-binding protein 1 (CRABP1) is a prognostic marker for adenocarcinoma and clear cell carcinoma that exhibits chemo-resistance. It is a is a modulator of retinoic acid and plays an important role in retinoic acid-mediated differentiation and proliferation processes. CRABP1 also functions as a tumor-suppressor in esophageal epithelium and its epigenetic silencing may play a pivotal role during esophageal carcinogenesis.

Physikalische Form

Solution in phosphate buffered saline containing 0.05% sodium azide.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: nwg
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)