C1240

Chlormethiazole hydrochloride

≥98% (HPLC), powder

• Synonym(e): 4-methyl-5-(β-chloroethyl)thiazole hydrochloride, 5-(2-Chloroethyl)-4-methylthiazole hydrochloride, Clomethiazole hydrochloride, Somnevrin hydrochloride
• Empirische Formel (Hill-System): C₆H₈ClNS · HCl
• CAS-Nummer: 6001-74-7
• Molekulargewicht: 198.11
• MDL-Nummer: MFCD00673948
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329774745
• NACRES: NA.77

Eigenschaften

• Beschreibung: Store desiccated
• Qualitätsniveau: 100
• Assay: ≥98% (HPLC)
• Form: powder
• Farbe: off-white
• Löslichkeit: H₂O: soluble >10 mg/mL
• Ersteller: AstraZeneca
• SMILES String: Cl.Cc1ncsc1CCCl
• InChI: 1S/C6H8ClNS.ClH/c1-5-6(2-3-7)9-4-8-5;/h4H,2-3H2,1H3;1H
• InChIKey: OFXYKSLKNMTBHK-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

Chlormethiazole serves as an anticonvulsant. It is useful in treating alcohol addiction and eclampsia. Chlormethiazole is also useful in treating convulsive status epilepticus. Long term administration of chlormethiazole leads to addiction to the drug.

GABA_A agonist; glycine receptor modulator.

Leistungsmerkmale und Vorteile

This compound is a featured product for ADME Tox and Neuroscience research. Discover more featured ADME Tox and Neuroscience products. Learn more about bioactive small molecules for other areas of research at sigma.com/discover-bsm.

This compound was developed by AstraZeneca. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H317,H318
• P-Sätze: P280 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 + P310
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Dam. 1 - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Faceshields, Gloves