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Merck

B9265

Sigma-Aldrich

Anti-Mouse IgM (μ-chain specific)–Biotin antibody produced in goat

affinity isolated antibody, buffered aqueous solution

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About This Item

MDL-Nummer:
UNSPSC-Code:
12352203
NACRES:
NA.46

Biologische Quelle

goat

Qualitätsniveau

Konjugat

biotin conjugate

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

secondary antibodies

Klon

polyclonal

Form

buffered aqueous solution

Methode(n)

direct ELISA: 1:20,000

Lagertemp.

2-8°C

Posttranslationale Modifikation Target

unmodified

Allgemeine Beschreibung

IgM is a glycoprotein antibody that regulates humoral immune responses. Mouse IgM is involved in modulating B cell memory . This antibody isotype has also been implicated in the development of autoimmune responses associated with the pathogenesis of type 1 diabetes in mice . Anti-Mouse IgM (μ-chain specific)-Biotin antibody is specific for mouse IgM when tested against mouse IgA, IgG, and IgM by ELISA.

Immunogen

Mouse IgM

Anwendung

Anti-Mouse IgM (μ-chain specific)-Biotin antibody is suitable for use in immunocytochemistry (at 1:500 dilutions in methanol-fixed, sheep embryo sections) and direct ELISA (1:20,000).

Physikalische Form

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 1% bovine serum albumin and 15 mM sodium azide

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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Xiangang Zou et al.
Journal of immunology (Baltimore, Md. : 1950), 170(3), 1354-1361 (2003-01-23)
Silencing individual C (constant region) lambda genes in a kappa(-/-) background reduces mature B cell levels, and L chain-deficient (lambda(-/-)kappa(-/-)) mice attain a complete block in B cell development at the stage when L chain rearrangement, resulting in surface IgM
Thea Shavlakadze et al.
Neuromuscular disorders : NMD, 15(2), 139-146 (2005-02-08)
Loss of the nerve supply to skeletal muscle results in a relentless loss of muscle mass (atrophy) over time. The ability of insulin-like growth factor-1 to reduce atrophy resulting from denervation was examined after transection of the sciatic nerve in
M Dattena et al.
Molecular reproduction and development, 73(1), 31-39 (2005-10-06)
This study was conducted to isolate, to culture, and to characterize embryonic cell lines from in vitro produced vitrified sheep blastocysts. Embryos were produced and vitrified at the expanded blastocyst stage. Ten inner cell masses arising from day 6-7 blastocysts
Christian Reichel et al.
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Follistatin, a myostatin-inhibiting protein, is prohibited according to chapter S4 of the "WADA 2019 List of Prohibited Substances and Methods". While currently no approved pharmaceutical formulations of follistatin are available, follistatin can be bought on the black market. Most of
J Côrte-Real et al.
Diabetologia, 55(6), 1761-1772 (2012-03-03)
We sought to determine whether the presence of natural autoreactive antibodies of B1a cell origin would play a role in the initiation of type 1 diabetes. We compared IgM repertoires and B1a cell compartments in NOD and C57BL/6 mice. Serum

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