B1436

BAX Inhibiting Peptide V5

≥97% (HPLC), lyophilized powder

• Synonym(e): BIP-V5
• Empirische Formel (Hill-System): C₂₇H₅₀N₆O₆S
• CAS-Nummer: 579492-81-2
• Molekulargewicht: 586.79
• MDL-Nummer: MFCD04974826
• UNSPSC-Code: 12352200
• NACRES: NA.32

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥97% (HPLC)
• Form: lyophilized powder
• Lagertemp.: −20°C
• InChI: 1S/C27H50N6O6S/c1-16(2)15-20(24(35)31-19(27(38)39)9-6-7-12-28)32-23(34)18(11-14-40-5)30-25(36)21-10-8-13-33(21)26(37)22(29)17(3)4/h16-22H,6-15,28-29H2,1-5H3,(H,30,36)(H,31,35)(H,32,34)(H,38,39)/t18-,19-,20-,21-,22-/m0/s1
• InChIKey: NHMUTADCTDDWPV-YFNVTMOMSA-N

Beschreibung

Amino Acid Sequence

Val-Pro-Met-Leu-Lys

Biochem./physiol. Wirkung

BAX Inhibiting Peptide V5 protects Bax against conformational changes and it also prevents mitochondrial translocation. In vitro analysis prove that peptide V5 prevents apoptosis, mediated by a number of agents including staurosporine, ultraviolet and anti-cancer drug.

Bax-mediated apoptosis inhibitor; membrane permeable pentapeptide based on the Ku70-Bax inhibiting domain.

Sonstige Hinweise

Lyophilized from 0.1% TFA in H2O

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)