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B0515

Sigma-Aldrich

Betamethason 17-Valerat

Synonym(e):

1,4-Pregnadien-11β,17α,21-triol-9α-fluor-16β-methyl-3,20-dion-17-valerat, 9α-Fluor-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion-17-valerat, 9α-Fluor-16β-methylprednisolon-17-valerat, Betnovat

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About This Item

Empirische Formel (Hill-System):
C27H37FO6
CAS-Nummer:
2152-44-5
Molekulargewicht:
476.58
Beilstein:
4240001
MDL-Nummer:
MFCD00867446
UNSPSC-Code:
12352200
PubChem Substanz-ID:
24891523
NACRES:
NA.77

Form

powder

Ersteller

Schering Plough

Lagertemp.

2-8°C

SMILES String

CCCCC(=O)O[C@@]1([C@@H](C)CC2C3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C)C(=O)CO

InChI

1S/C27H37FO6/c1-5-6-7-23(33)34-27(22(32)15-29)16(2)12-20-19-9-8-17-13-18(30)10-11-24(17,3)26(19,28)21(31)14-25(20,27)4/h10-11,13,16,19-21,29,31H,5-9,12,14-15H2,1-4H3/t16-,19?,20?,21-,24-,25-,26-,27-/m0/s1

InChIKey

SNHRLVCMMWUAJD-QDHNOTTGSA-N

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Biochem./physiol. Wirkung

Betamethasone 17-valerate is a synthetic glucocorticoid. It exhibitstherapeutic effects against various allergic and inflammatory skin diseases. Betamethasone 17-valerate also possesses anti-inflammatory properties.

Leistungsmerkmale und Vorteile

This compound was developed by Schering Plough. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Piktogramme

Health hazard
GHS08

Signalwort

Danger

H-Sätze

H360FD,H373

Gefahreneinstufungen

Repr. 1B - STOT RE 2

Lagerklassenschlüssel

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 2

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Sigma-Aldrich

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Sorbinsäure 99.0-101.0% anhydrous basis

Sigma-Aldrich

S1626

Sorbinsäure

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Sigma-Aldrich

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Ameisensäure

Luigi Naldi et al.
American journal of clinical dermatology, 12(3), 191-201 (2011-02-03)
Corticosteroids are a versatile option for the treatment of mild-to-moderate psoriasis due to their availability in a wide range of potencies and formulations. Occlusion of the corticosteroid is a widely accepted procedure to enhance the penetration of the medication, thereby
Jin Zhang et al.
Journal of pharmaceutical sciences, 100(3), 896-903 (2010-09-15)
Corticosteroids are therapeutic agents widely used in the pharmacological treatment of skin diseases such as eczema or psoriasis. Unfortunately, their use is restricted by the side effects that frequently occur at the systemic level. The goal of the research described
Jayalakshmi Somuramasami et al.
Journal of pharmaceutical and biomedical analysis, 54(1), 242-247 (2010-09-11)
Currently, there are no analytical methods available in the literature that can simultaneously separate and quantitate residual levels of acetone, methylene chloride, n-butyl ether and dimethylsulfoxide in Betamethasone valerate active pharmaceutical ingredient (API). This paper describes the development and validation
Rosita Saraceno et al.
The Journal of dermatological treatment, 21(6), 363-366 (2010-06-12)
Prurigo nodularis is a distressing condition characterized by the presence of multiple nodules associated with intense pruritus. To assess the clinical efficacy and safety of betamethasone valerate 0.1% tape and a moisturizing itch-relief cream in prurigo nodularis. Twelve patients were
Paiboon Sookpotarom et al.
Pediatric surgery international, 29(4), 393-396 (2013-01-08)
0.05 % betamethasone valerate cream is generally used as an alternative to circumcision for the treatment of phimosis in boys. The aim of this study is to determine whether the half-strength formula (0.025 %) of betamethasone is as effective as 0.05 % betamethasone.
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