A7785
Apolipoprotein C-I from human plasma
≥95% (SDS-PAGE), lyophilized powder
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About This Item
Empfohlene Produkte
Biologische Quelle
human
Qualitätsniveau
Assay
≥95% (SDS-PAGE)
Form
lyophilized powder
Mol-Gew.
average mol wt 6.6 kDa
Methode(n)
inhibition assay: suitable
UniProt-Hinterlegungsnummer
Lagertemp.
−20°C
Angaben zum Gen
human ... APOC1(341)
Allgemeine Beschreibung
Very low density lipoprotein.
Anwendung
Apolipoprotein C-1 directly interferes with fatty acid uptake and is a major plasma inhibitor of cholesterol ester transfer protein. Apolipoprotein C-I has been used to develop a quantitative strategy, named secretome-derived isotopic tag (SDIT), to concurrently identify and quantify the adipocyte-secreted plasma proteins from normal and high-fat-diet (HFD) induced obese mice.
Biochem./physiol. Wirkung
Interferes directly with fatty acid uptake and is the major plasma inhibitor of cholesterol ester transfer protein.
Physikalische Form
Lyophilized from 10 mM NH4HCO3, pH 7.5
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
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B S Suri et al.
The Biochemical journal, 178(2), 455-466 (1979-02-15)
1. The work reported was designed to provide quantitative information about the capacity of the extrahepatic tissues of the rat to degrade injected VLD lipoproteins (very-low-density lipoproteins, d less than 1.006) to LD lipoproteins (low-density lipoproteins, d 1.006--1.063) and to
Rong-Xia Li et al.
Journal of proteome research, 11(5), 2851-2862 (2012-03-13)
We developed a quantitative strategy, named secretome-derived isotopic tag (SDIT), to concurrently identify and quantify the adipocyte-secreted plasma proteins from normal and high-fat-diet (HFD) induced obese mice, based on the application of isotope-labeled secreted proteins from cultured mouse adipocytes as
Nathan L Meyers et al.
Biochemistry, 51(6), 1238-1248 (2012-01-24)
Apolipoprotein C-I (apoC-I) is an important constituent of high-density lipoprotein (HDL) and is involved in the accumulation of cholesterol ester in nascent HDL via inhibition of cholesterol ester transfer protein and potential activation of lecithin:cholesterol acyltransferase (LCAT). As the smallest
Artikel
Since cholesterol is a water-insoluble molecule it must be packaged for transport within the plasma. The particles that package cholesterol, cholesteryl esters, and triglycerides for transport, are called lipoproteins.
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