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A5560

Sigma-Aldrich

Anti-Water Channel Aquaporin 1 antibody produced in rabbit

IgG fraction of antiserum, lyophilized powder

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About This Item

MDL-Nummer:
MFCD02262541
UNSPSC-Code:
12352203
PubChem Substanz-ID:
24890993
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100

Konjugat

unconjugated

Antikörperform

IgG fraction of antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Form

lyophilized powder

Speziesreaktivität

rat, human

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot (chemiluminescent): 1:400-1:800

UniProt-Hinterlegungsnummer

P29972

Lagertemp.

−20°C

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... AQP1(358)
rat ... Aqp1(25240)

Allgemeine Beschreibung

Aquaporins are transmembrane proteins composed of 6 α helices that regulate the flow of water across the membrane. AQP1 is highly expressed on the apical membrane of kidneys.
Rabbit Anti-Water Channel Aquaporin 1 antibody binds to human and rat aquaporin 1.

Immunogen

synthetic peptide corresponding to amino acids 243-261 of human aquaporin 1 conjugated to KLH with glutaraldehyde. The epitope is identical in human, rodent, and cattle and only slightly different in frog.

Anwendung

Rabbit Anti-Water Channel Aquaporin 1 antibody has been used for immunocytochemical assays. The product can also be used for immunohistochemistry and western blot.

Physikalische Form

Lyophilized from phosphate buffered saline, pH 7.4, and 0.025% sodium azide

Angaben zur Herstellung

Isolated on immobilized Protein A

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

Elisabeth Kruse et al.
Genome biology, 7(2), 206-206 (2006-03-09)
Water is the major component of all living cells, and efficient regulation of water homeostasis is essential for many biological processes. The mechanism by which water passes through biological membranes was a matter of debate until the discovery of the
Kamila Foguesatto et al.
Cell biology international, 46(6), 976-985 (2022-03-09)
The physiological variations during the crustacean molting cycle have intrigued researchers for many years. Maintaining osmotic homeostasis in the face of hemolymph dilution and dealing with dynamic intracellular and extracellular calcium fluctuations are challenges these animals continuously confront. It has
R T Boyle et al.
Bulletin of environmental contamination and toxicology, 90(3), 387-390 (2013-01-01)
We used immunocytochemical and fluorometric techniques to show that gill cells of two marine invertebrates, the crab Neohelice granulata (osmoregulator) and the clam Mesodesma mactroides (osmoconformer), increase the expression of membrane transporters [Na(+)/K(+)-ATPase and aquaporin (AQP1)] after whole-animals exposure (96 h)
Caroline T Rocha et al.
Archives of environmental contamination and toxicology, 62(1), 56-67 (2011-04-29)
The objective of this study was to evaluate the influence of lead (Pb) on regulatory proteins linked to mechanisms of animal adaptation to polluted environments (using in vivo and in vitro tests) and to validate the in vitro assay as
Esperanza Gonzalez et al.
International journal of biological sciences, 17(8), 1864-1877 (2021-06-17)
Alcohol abuse has a high impact on the mortality and morbidity related to a great number of diseases and is responsible for the development of alcoholic liver disease (ALD). It remains challenging to detect and evaluate its severity, which is
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