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A1263

Sigma-Aldrich

DL-Amphetamin -sulfat (Salz)

Synonym(e):

(±)-α-Methylphenethylamine sulfate salt

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About This Item

Lineare Formel:
C18H26N2 · H2SO4
CAS-Nummer:
60-13-9
Molekulargewicht:
368.49
EG-Nummer:
200-457-8
MDL-Nummer:
MFCD00070254
UNSPSC-Code:
12352116
PubChem Substanz-ID:
329770696
NACRES:
NA.77

Form

powder

Qualitätsniveau

100

Arzneimittelkontrolle

USDEA Schedule II; Home Office Schedule 2; stupéfiant (France); kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada

Anwendung(en)

forensics and toxicology

SMILES String

OS(O)(=O)=O.CC(N)Cc1ccccc1.CC(N)Cc2ccccc2

InChI

1S/2C9H13N.H2O4S/c2*1-8(10)7-9-5-3-2-4-6-9;1-5(2,3)4/h2*2-6,8H,7,10H2,1H3;(H2,1,2,3,4)

InChIKey

PYHRZPFZZDCOPH-UHFFFAOYSA-N

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Anwendung

DL-Amphetamine sulfate salt has been used to induce place preference in rats to study the effect of diazepam and zolpidem. It has also been used as a drug standard in the digital image-based colorimetric presumptive test.

Biochem./physiol. Wirkung

DL -Amphetamine, also known as benzedrine, is a synthetic stimulant. It is usually produced as a sulfate salt (DL-amphetamine sulfate salt). DL-Amphetamine sulfate may be used to treat children with behavior disorders., Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake.

Piktogramme

Skull and crossbonesHealth hazard
GHS06,GHS08

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 2 Inhalation - Acute Tox. 2 Oral - Aquatic Chronic 3 - Repr. 2 - STOT RE 2 - STOT SE 3

Zielorgane

Brain, Respiratory system

Lagerklassenschlüssel

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges

Analysenzertifikate (COA)

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Madeleine P Strohl
The Yale journal of biology and medicine, 84(1), 27-33 (2011-04-01)
In 1937, psychiatrist Charles Bradley administered Benzedrine sulfate, an amphetamine, to "problem" children at the Emma Pendleton Bradley Home in Providence, Rhode Island, in an attempt to alleviate headaches; however, Bradley noticed an unexpected effect upon the behavior of the
Rita Perfeito et al.
Free radical biology & medicine, 62, 186-201 (2013-06-08)
Parkinson disease (PD) is a chronic and progressive neurological disease associated with a loss of dopaminergic neurons. In most cases the disease is sporadic but genetically inherited cases also exist. One of the major pathological features of PD is the
Mark A Sembower et al.
Journal of addictive diseases, 32(1), 26-38 (2013-03-14)
This article examines rates of nonmedical use and diversion of extended-release amphetamine and extended-release oral methylphenidate in the United States. Prescription dispensing data were sourced from retail pharmacies. Nonmedical use data were collected from the Researched Abuse, Diversion and Addiction-Related
Meagan L Auger et al.
The European journal of neuroscience, 38(6), 2853-2863 (2013-06-07)
DCC and UNC5 homologs (UNC5H) are guidance cue receptors highly expressed by mesocorticolimbic dopamine neurons. We have shown that dcc heterozygous mice exhibit increased dopamine, but not norepinephrine, innervation and function in medial prefrontal cortex. Concomitantly, dcc heterozygotes show blunted
Maria Xilouri et al.
Brain : a journal of neurology, 136(Pt 7), 2130-2146 (2013-06-13)
α-Synuclein levels are critical to Parkinson's disease pathogenesis. Wild-type α-synuclein is degraded partly by chaperone-mediated autophagy, and aberrant α-synuclein may act as an inhibitor of the pathway. To address whether the induction of chaperone-mediated autophagy may represent a potential therapy
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