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78264

Sigma-Aldrich

7-Diethylamino-3-[4-(Jodacetamido)phenyl]-4-Methylcumarin

BioReagent, suitable for fluorescence, ≥85% (HPLC)

Synonym(e):

DCIA

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About This Item

Empirische Formel (Hill-System):
C22H23IN2O3
CAS-Nummer:
76877-34-4
Molekulargewicht:
490.33
MDL-Nummer:
MFCD00467581
UNSPSC-Code:
12352200
PubChem Substanz-ID:
329768132
NACRES:
NA.31

Produktlinie

BioReagent

Assay

≥85% (HPLC)

Form

crystals

Fluoreszenz

λex 389 nm; λem 467 nm in methanol

Eignung

suitable for fluorescence

SMILES String

CCN(CC)c1ccc2C(C)=C(C(=O)Oc2c1)c3ccc(NC(=O)CI)cc3

InChI

1S/C22H23IN2O3/c1-4-25(5-2)17-10-11-18-14(3)21(22(27)28-19(18)12-17)15-6-8-16(9-7-15)24-20(26)13-23/h6-12H,4-5,13H2,1-3H3,(H,24,26)

InChIKey

WIXAQXKQLNRFDF-UHFFFAOYSA-N

Piktogramme

Skull and crossbones
GHS06

Signalwort

Danger

H-Sätze

H301,H413

Gefahreneinstufungen

Acute Tox. 3 Oral - Aquatic Chronic 4

Lagerklassenschlüssel

6.1D - Non-combustible acute toxic Cat.3 / toxic hazardous materials or hazardous materials causing chronic effects

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

dust mask type N95 (US), Eyeshields, Faceshields, Gloves

Analysenzertifikate (COA)

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I D Clark et al.
Analytical biochemistry, 213(2), 296-302 (1993-09-01)
In this study a Ca(2+)-binding 14mer peptide was synthesized with the sequence GDKNADGCIEFEEL, allowing covalent attachment of sulfhydryl-reactive fluorescent molecules at position 7 of the 12-residue, metal-binding loop (underlined). This provided the opportunity to select donor molecules with suitable spectral
Carsten Rendenbach et al.
Microsurgery, 39(4), 304-309 (2018-08-31)
Free flap surgery can be associated with donor-site morbidity. The purpose of this study was to analyze long-term functional outcomes at the donor site after deep circumflex iliac artery (DCIA) bone flap harvesting. Fourteen patients (8 men and 6 women
T O Sippel
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, 29(2), 314-316 (1981-02-01)
N-(4-(7 - Diethylamino - methylcoumarin - 3 yl)phenyl)maleimide (CPM) and the corresponding iodoacetamide are described. When applied to sections at pH 6 and 9, respectively, the two fluorogens are very similar in their reactivity and selectivity toward thiols with which
W D Picking et al.
Biochemistry, 31(8), 2368-2375 (1992-03-03)
The fate of the amino termini of nascent polyalanine, polyserine, and polylysine was monitored by fluorescence techniques as each was translated on Escherichia coli ribosomes. A coumarin probe was placed at the alpha-amino group of a synthetic elongator alanyl-tRNA or
Mélodie Duval et al.
Methods (San Diego, Calif.), 117, 48-58 (2016-12-29)
RNA-protein interactions are at the bases of many biological processes, forming either tight and stable functional ribonucleoprotein (RNP) complexes (i.e. the ribosome) or transitory ones, such as the complexes involving RNA chaperone proteins. To localize the sites where a protein
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