62962

3-sn-Lysophosphatidylcholin

egg yolk, ≥99.0% (TLC)

• Synonym(e): L-α-Lysolecithin, L-α-Lysophosphatidylcholin
• MDL-Nummer: MFCD00131444
• UNSPSC-Code: 51321705
• NACRES: NA.25

Eigenschaften

• Biologische Quelle: egg yolk
• Beschreibung: zwitterionic
• Assay: ≥99.0% (TLC)
• Form: powder or solid
• Zusammensetzung: 16:0, ~69% (fatty acid); 18:0, ~27% (fatty acid); 18:1, ~3% (fatty acid)
• Löslichkeit: chloroform/methanol: 50 mg/mL, clear, colorless to very faintly yellow
• Funktionelle Gruppe: phospholipid
• Lipid-Typ: phosphoglycerides
• Versandbedingung: wet ice
• Lagertemp.: −20°C

Beschreibung

Anwendung

• The activation mode of the mechanosensitive ion channel, MscL, by lysophosphatidylcholine differs from tension-induced gating: L-α-LPC is explored for its unique interaction with ion channels, suggesting its potential as a tool for studying channel mechanics and developing new therapeutic strategies for diseases linked to cellular mechanics (Mukherjee et al., 2014).


• Aerosol delivery of an enhanced helper-dependent adenovirus formulation to rabbit lung using an intratracheal catheter: The use of L-α-LPC in enhancing the delivery of gene therapy vectors via aerosol demonstrates its utility in improving the efficiency of gene therapies, particularly for respiratory diseases (Koehler et al., 2005).

Biochem./physiol. Wirkung

3-sn-Lysophosphatidylcholine, besides contributing to the positive curvature of membranes , inhibits SNARE complex disassembly in vitro and in rat nerve terminals and exocrine pancrease .

Sonstige Hinweise

Preparation of demembranated frog sperm chromatin

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, type N95 (US)