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Merck

462R-1

Sigma-Aldrich

SF-1 (EP434) Rabbit Monoclonal Primary Antibody

Synonym(e):

Steroidogenic Factor-1

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203

Biologische Quelle

rabbit

Qualitätsniveau

100
500

Konjugat

unconjugated

Antikörperform

culture supernatant

Antikörper-Produkttyp

primary antibodies

Klon

EP434, monoclonal

Beschreibung

For In Vitro Diagnostic Use in Select Regions

Form

buffered aqueous solution

Speziesreaktivität

human

Verpackung

vial of 0.1 mL concentrate (462R-14)
vial of 0.1 mL concentrate Research Use Only (462R-14-RUO)
vial of 0.5 mL concentrate (462R-15)
vial of 1.0 mL concentrate (462R-16)
vial of 1.0 mL concentrate Research Use Only (462R-16-RUO)
vial of 1.0 mL pre-dilute Research Use Only (462R-17-RUO)
vial of 1.0 mL pre-dilute ready-to-use (462R-17)
vial of 7.0 mL pre-dilute ready-to-use (462R-18)
vial of 7.0 mL pre-dilute ready-to-use Research Use Only (462R-18-RUO)

Hersteller/Markenname

Cell Marque

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:25-1:100 (concentrated)

Isotyp

IgG

Kontrolle

adrenocortical carcionma, granulosa cell tumor, testis

Versandbedingung

wet ice

Lagertemp.

2-8°C

Visualisierung

nuclear

Angaben zum Gen

human ... SF1(7536)

Allgemeine Beschreibung

As both a nuclear receptor and nuclear transcription factor, Steroidogenic factor-1 (SF-1) serves as an important modulator of steroidogenesis. It has been demonstrated that SF-1 serves as a “master regulator” in varying facets of development and function in both reproductive and adrenal tissues. Immunohistochemical detection of SF-1 in testicular tissue may provide value for distinguishing sex-cord stromal tumors, including Leydig cell, Sertoli cell and granulosa cell neoplasms, from other tumors. In addition, SF-1 detection may have utility in distinguishing primary adrenal cortical lesions from their histologic mimics such as renal clear cell carcinoma.

Qualität


IVD

IVD

IVD

RUO

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide.

Angaben zur Herstellung

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Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2


Analysenzertifikate (COA)

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Ranna El-Khairi et al.
Seminars in reproductive medicine, 30(5), 374-381 (2012-10-10)
Steroidogenic factor-1 (SF-1) (Ad4BP, NR5A1) is a nuclear receptor that plays a key role in adrenal and reproductive development and function. Deletion of the gene encoding Sf-1 (Nr5a1) in mice results in severe developmental defects of the adrenal gland and
Ankur R Sangoi et al.
The American journal of surgical pathology, 35(5), 678-686 (2011-04-15)
The diagnosis of metastatic clear cell renal cell carcinoma (CC-RCC) can be difficult because of its morphologic heterogeneity and the increasing use of small image-guided biopsies that yield scant diagnostic material. This is further complicated by the degree of morphologic

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