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Merck

318A-1

Sigma-Aldrich

PGP 9.5 Rabbit Polyclonal Antibody

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100
500

Konjugat

unconjugated

Antikörperform

Ig fraction of antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Beschreibung

For In Vitro Diagnostic Use in Select Regions (See Chart)

Form

buffered aqueous solution

Speziesreaktivität

human

Verpackung

vial of 0.1 mL concentrate (318A-14)
vial of 0.5 mL concentrate (318A-15)
bottle of 1.0 mL predilute (318A-17)
vial of 1.0 mL concentrate (318A-16)
bottle of 7.0 mL predilute (318A-18)

Hersteller/Markenname

Cell Marque

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500

Kontrolle

nerve tissue

Versandbedingung

wet ice

Lagertemp.

2-8°C

Visualisierung

cytoplasmic

Allgemeine Beschreibung

Protein gene product 9.5 (PGP 9.5), also known as ubiquitin carboxyl-terminal hydrolase-1 (UCHL-1), is a 27 kDa protein originally isolated from whole brain extracts. Although PGP 9.5 expression in normal tissues was originally felt to be strictly confined to neurons and neuroendocrine cells, it has been subsequently documented in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. A plethora of mesenchymal neoplasms have demonstrated PGP 9.5 expression.

Qualität


IVD

IVD

IVD

RUO

Verlinkung

PGP9.5 Positive Control Slides, Product No. 318S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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M Mahalingam et al.
Journal of cutaneous pathology, 33(1), 51-56 (2006-01-31)
Cellular neurothekeoma is a relatively rare, benign cutaneous neoplasm, which usually presents as a solitary papule or nodule involving the head and neck area of young adults. Multiple neurothekeomas have not, to date, been known to occur. We report a
M Mahalingam et al.
Journal of cutaneous pathology, 28(6), 282-286 (2001-06-13)
Protein gene product 9.5 (PGP 9.5) is expressed in brain at 20 to 50 times the levels detected in other organs. Immunohistochemical studies reveal this protein is localized to both central and peripheral neurons. Recently, PGP 9.5 is reported to
Lucas K Campbell et al.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, 16(10), 963-969 (2003-10-16)
In non-neoplastic tissues, the expression of protein gene product 9.5 (PGP 9.5), a member of the ubiquitin hydrolase family of proteins, is confined to neural and neuroendocrine cells. Although it has been claimed that PGP 9.5 is a specific marker
G Bassotti et al.
Journal of clinical pathology, 58(9), 973-977 (2005-08-30)
Colonic diverticular disease (diverticulosis) is a common disorder in Western countries. Although its pathogenesis is probably multifactorial, motor abnormalities of the large bowel are thought to play an important role. However, little is known about the basic mechanism that may

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