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Merck

306M-2

Sigma-Aldrich

NSE (MRQ-55) Mouse Monoclonal Antibody

Anmeldenzur Ansicht organisationsspezifischer und vertraglich vereinbarter Preise


About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100
500

Konjugat

unconjugated

Antikörperform

culture supernatant

Antikörper-Produkttyp

primary antibodies

Klon

MRQ-55, monoclonal

Beschreibung

For In Vitro Diagnostic Use in Select Regions (See Chart)

Form

buffered aqueous solution

Speziesreaktivität

human

Verpackung

vial of 0.1 mL concentrate (306M-24)
vial of 0.5 mL concentrate (306M-25)
bottle of 1.0 mL predilute (306M-27)
vial of 1.0 mL concentrate (306M-26)
bottle of 7.0 mL predilute (306M-28)

Hersteller/Markenname

Cell Marque

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Isotyp

IgG2b

Kontrolle

appendix/colon, schwannoma

Versandbedingung

wet ice

Lagertemp.

2-8°C

Visualisierung

cytoplasmic

Angaben zum Gen

human ... ENO2(2026)

Allgemeine Beschreibung

Neuron-specific enolase (NSE) is a glycolytic isoenzyme of the enolase gamma-gamma dimerselectively detected in neurons, peripheral nerves, some neuroendocrine cells, and tumors.NSE immunoreactivity is also observed, to a lesser extent, in smooth muscle tissue. Anti-NSEis often used to visualize peripheral nerves and for the identification of neuroendocrinedifferentiation.

Qualität


IVD

IVD

IVD

RUO

Verlinkung

NSE Positive Control Slides, Product No. 306S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


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N Leonard et al.
Gut, 37(6), 763-765 (1995-12-01)
The pathogenesis of villous damage in coeliac disease is unknown. Change to the delicate neuromuscular core may be significant and this study stained various categories of coeliac disease and controls with neuron-specific enolase (NSE) to examine neurofilaments in the mucosa.
M R Wick et al.
American journal of clinical pathology, 79(6), 703-707 (1983-06-01)
In order to better define the use of neuron-specific enolase (NSE) as a marker for neuroendocrine neoplasms, we studied 11 thymic carcinoid tumors, three bronchial small-cell carcinomas (all with cutaneous metastases), and 10 trabecular carcinomas of the skin for its
A S Leong et al.
Pathology, 18(4), 393-399 (1986-10-01)
Thirteen cases of primary endocrine carcinoma of the skin (Merkel cell carcinoma) were reviewed with the aim of defining the morphological, immunohistochemical and ultrastructural criteria for diagnosis. The tumour cells were characterized by their scanty cytoplasm, generally small uniform nuclei
E H Cooper
The International journal of biological markers, 9(4), 205-210 (1994-10-01)
The clinical value of neuron-specific enolase as a marker is small cell lung cancer, neuroblastoma, melanoma and seminoma has been reviewed. The role of serum and cerebrospinal NSE in benign and malignant disease of the central nervous system is discussed.
S A Vinores et al.
Archives of pathology & laboratory medicine, 108(7), 536-540 (1984-07-01)
In normal conditions, neuron-specific enolase (NSE) is histochemically demonstrable only in neurons and cells of the amine precursor uptake and decarboxylation (APUD) system. This has been found not to be true for neoplastic cells. Several types of CNS tumors, including

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