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Key Documents

297A-7

Sigma-Aldrich

Myoglobin Rabbit Polyclonal Antibody

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About This Item

UNSPSC-Code:
12352203
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

100
500

Konjugat

unconjugated

Antikörperform

Ig fraction of antiserum

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Beschreibung

For In Vitro Diagnostic Use in Select Regions (See Chart)

Form

buffered aqueous solution

Speziesreaktivität

human

Verpackung

vial of 0.1 mL concentrate (297A-74)
vial of 0.5 mL concentrate (297A-75)
bottle of 1.0 mL predilute (297A-77)
vial of 1.0 mL concentrate (297A-76)
bottle of 7.0 mL predilute (297A-78)

Hersteller/Markenname

Cell Marque™

Methode(n)

immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:200

Kontrolle

skeletal muscle

Versandbedingung

wet ice

Lagertemp.

2-8°C

Visualisierung

cytoplasmic

Angaben zum Gen

human ... MB(4151)

Allgemeine Beschreibung

Immunostaining with anti-myoglobin provides a specific, sensitive, and practical procedure for the identification of tumors of muscle origin. Since myoglobin is found exclusively in skeletal and cardiac muscle and is not present in any other cells of the human body, it may be used to distinguish rhabdomyosarcoma from other soft tissue tumors. Anti-myoglobin staining is also useful when demonstrating rhabdomyoblastic differentiation in other tumors, e.g. neurogenic sarcomas and malignant mixed mesodermal tumors of the uterus and ovary.

Qualität


IVD
IVD
IVD
RUO

Verlinkung

Myoglobin Positive Control Slides, Product No. 297S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Physikalische Form

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

Angaben zur Herstellung

Download the IFU specific to your product lot and formatNote: This requires a keycode which can be found on your packaging or product label.

Sonstige Hinweise

For Technical Service please contact: 800-665-7284 or email: service@cellmarque.com

Rechtliche Hinweise

Cell Marque is a trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

L G Kindblom et al.
Acta pathologica, microbiologica, et immunologica Scandinavica. Section A, Pathology, 90(3), 167-174 (1982-05-01)
An immuno-histochemical investigation of the presence and localization of myoglobin was performed on cardiac and skeletal muscle tissue and on 9 embryonal and 9 alveolar rhabdomyosarcomas, utilizing an immunoperoxidase technique. Cardiac muscle fibres were evenly stained whereas staining of skeletal
H J Kahn et al.
Cancer, 51(10), 1897-1903 (1983-05-15)
Histologic examination was carried out in 65 cases of childhood rhabdomyosarcoma (RMS), 53 embryonal, and 12 alveolar. Cross-striations were seen on light microscopy in 12 (23%) embryonal and 4 (33%) alveolar tumors. The capacity of immunohistochemical staining (PAP technique) to
J M Corson et al.
The American journal of pathology, 103(3), 384-389 (1981-06-01)
Intracellular myoglobin represents an excellent marker for specific characterization of normal (adult and fetal) and malignant skeletal muscle cells in paraffin sections. With an immunoperoxidase indirect sandwich technique for detection of intracellular myoglobin, positive staining was observed in 13 of
J J Brooks
Cancer, 50(9), 1757-1763 (1982-11-01)
Myoglobin, found exclusively in striated muscle, can be considered a fetal antigen. This study investigated its usefulness as a tumor marker for rhabdomyosarcoma (RMS) using an immunoperoxidase technique. Eight-nine percent (89%) or 27 rhabdomyosarcomas contained immunoreactive myoglobin. In contrast, all
K Mukai et al.
The American journal of surgical pathology, 3(4), 373-376 (1979-08-01)
Using an immunoperoxidase method, myoglobin is localized in the cytoplasm of normal and neoplastic human skeletal muscle. The staining intensity is variable in individual cells. This can be explained by the variable concentration of myoglobin in the different fiber types
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