Y0001413

Fulvestrant für die Systemeignung

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): Fulvestrant, (7α,17β)-7-[9-[(4,4,5,5,5-Pentafluorpentyl)sulfinyl]nonyl]estra-1,3,5(10)-trien-3,17-diol, Faslodex, ICI 182.780, ZD 182780, ZD 9238, ZM 182780
• Empirische Formel (Hill-System): C₃₂H₄₇F₅O₃S
• CAS-Nummer: 129453-61-8
• Molekulargewicht: 606.77
• MDL-Nummer: MFCD00903953
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329831412
• NACRES: NA.24

Eigenschaften

• Qualität: pharmaceutical primary standard
• API-Familie: fulvestrant
• Hersteller/Markenname: EDQM
• Anwendung(en): pharmaceutical (small molecule)
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: [H][C@]12CC[C@]3(C)[C@@H](O)CC[C@@]3([H])[C@]1([H])[C@H](CCCCCCCCCS(=O)CCCC(F)(F)C(F)(F)F)Cc4cc(O)ccc24
• InChI: 1S/C32H47F5O3S/c1-30-17-15-26-25-12-11-24(38)21-23(25)20-22(29(26)27(30)13-14-28(30)39)10-7-5-3-2-4-6-8-18-41(40)19-9-16-31(33,34)32(35,36)37/h11-12,21-22,26-29,38-39H,2-10,13-20H2,1H3/t22-,26-,27+,28+,29-,30+,41?/m1/s1
• InChIKey: VWUXBMIQPBEWFH-WCCTWKNTSA-N
• Angaben zum Gen: human ... ESR1(2099) , ESR2(2100)

Beschreibung

Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Fulvestrant for system suitability EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Biochem./physiol. Wirkung

Fulvestrant (ICI 182.780) ist ein selektiver Östrogenrezeptor-Herunterregulator (SERD). Fulvestrant ist ein hochaffiner Östrogenrezeptor-Antagonist. IC₅₀ = 0,29 nM. Fulvestrant ist das erste „reine“ Antiöstrogen, das keine agonistische Wirkung hat, sowohl in vitro als auch in vivo.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

Sicherheitshinweise

• Piktogramme: GHS08,GHS09
• Signalwort: Danger
• H-Sätze: H360Df,H362,H410
• P-Sätze: P202 - P260 - P263 - P264 - P273 - P308 + P313
• Gefahreneinstufungen: Aquatic Chronic 1 - Lact. - Repr. 1B
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable