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Y0000821

Molsidomin

European Pharmacopoeia (EP) Reference Standard

Synonym(e):

N-(Ethoxycarbonyl)-3-morpholinosydnonimin

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About This Item

Empirische Formel (Hill-System):
C9H14N4O4
CAS-Nummer:
25717-80-0
Molekulargewicht:
242.23
MDL-Nummer:
MFCD00869301
UNSPSC-Code:
41116107
PubChem Substanz-ID:
329831170
NACRES:
NA.24

Qualität

pharmaceutical primary standard

API-Familie

molsidomine

Hersteller/Markenname

EDQM

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

SMILES String

CCOC(=O)N=C1O[N-][N+](=C1)N2CCOCC2

InChI

1S/C9H14N4O4/c1-2-16-9(14)10-8-7-13(11-17-8)12-3-5-15-6-4-12/h7H,2-6H2,1H3/b10-8-

InChIKey

XLFWDASMENKTKL-NTMALXAHSA-N

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Allgemeine Beschreibung

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

Anwendung

Molsidomine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia.

Verpackung

The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue.

Sonstige Hinweise

Sales restrictions may apply.

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Piktogramme

Exclamation mark
GHS07

Signalwort

Warning

H-Sätze

H302

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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Effects of molsidomine and other NO-containing vasodilators on cyclic GMP formation.
E Böhme et al.
European heart journal, 4 Suppl C, 19-24 (1983-05-01)
[Nitric oxide in therapy of angina pectoris: nitrates or molsidomine?].
V Schächinger et al.
Der Internist, 38(5), 438-447 (1997-05-01)
J L Wautier
Presse medicale (Paris, France : 1983), 17(20), 1037-1040 (1988-05-25)
Platelet suppressive agents have been shown to improve the prognosis of coronary diseases such as myocardial infarction and unstable angina. Several markers of platelet activation during myocardial ischemia have been found to be increased. Platelet granule constituents (beta thromboglobulin or
Cardiovascular pharmacology of molsidomine.
O Thulesius
Bibliotheca cardiologica, (38)(38), 234-243 (1984-01-01)
E Singlas et al.
Annales de cardiologie et d'angeiologie, 32(8), 503-509 (1983-12-01)
Molsidomine is well absorbed by the gastro-intestinal tract and is taken up by the liver during the first passage. Its bioavailability is 60 per cent. Digestive or sublingual absorption is rapid: maximal plasma concentrations are obtained 0.5 to 1.0 hours
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