SMB01383

PhIP

≥95% (HPLC)

• Synonym(e): 2-Amino-1-methyl-6-phenylimidazo[4,5-b]pyridine
• Empirische Formel (Hill-System): C₁₃H₁₂N₄
• CAS-Nummer: 105650-23-5
• Molekulargewicht: 224.26
• MDL-Nummer: MFCD00210745
• UNSPSC-Code: 12352100
• NACRES: NA.28

Eigenschaften

• Biologische Quelle: synthetic
• Qualitätsniveau: 200
• Assay: ≥95% (HPLC)
• Form: solid
• Versandbedingung: 2-8°C
• Lagertemp.: 2-8°C
• SMILES String: NC1=NC2=NC=C(C3=CC=CC=C3)C=C2N1C

Beschreibung

Allgemeine Beschreibung

PhIP (2-Amino-1-methyl-6-phenylimidazo(4,5-b)pyridine) is a dietary genotoxic carcinogen formed in heat processed meat and fish via the Maillard reaction. PhIP is a primary metabolite activated by CYP1A2 and N-acetyltransferase 1 or sulfotransferase to DNA reactive metabolite.

Biochem./physiol. Wirkung

Carcinogen developed in grilled meats. Induces breast and colon cancer in rats.

Sicherheitshinweise

• Piktogramme: GHS06,GHS08
• Signalwort: Danger
• H-Sätze: H301,H315,H319,H335,H351
• P-Sätze: P202 - P261 - P264 - P301 + P310 - P302 + P352 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 3 Oral - Carc. 2 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable