PHR2099

Cefotaxim Natriumsalz

Pharmaceutical Secondary Standard; Certified Reference Material

• Synonym(e): Cefotaxime Natriumsalz
• Empirische Formel (Hill-System): C₁₆H₁₆N₅NaO₇S₂
• CAS-Nummer: 64485-93-4
• Molekulargewicht: 477.45
• Beilstein: 5711411
• MDL-Nummer: MFCD00079073
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: certified reference material; pharmaceutical secondary standard
• Qualitätsniveau: 300
• Agentur: traceable to Ph. Eur. C0685000; traceable to USP 1097909
• API-Familie: cefotaxime
• Form: powder
• Analysenzertifikat (CofA): current certificate can be downloaded
• Verpackung: pkg of 1 g
• Anwendung(en): pharmaceutical small molecule
• Lagertemp.: 2-8°C
• SMILES String: [Na+].[H][C@]12SCC(COC(C)=O)=C(N1C(=O)[C@H]2NC(=O)C(=N/OC)\c3csc(N)n3)C([O-])=O
• InChI: 1S/C16H17N5O7S2.Na/c1-6(22)28-3-7-4-29-14-10(13(24)21(14)11(7)15(25)26)19-12(23)9(20-27-2)8-5-30-16(17)18-8;/h5,10,14H,3-4H2,1-2H3,(H2,17,18)(H,19,23)(H,25,26);/q;+1/p-1/b20-9-;/t10-,14-;/m1./s1
• InChIKey: AZZMGZXNTDTSME-JUZDKLSSSA-M

Beschreibung

Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards

Anwendung

These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Biochem./physiol. Wirkung

Cefotaxim hemmt die bakterielle Zellwand-Synthese durch Bindung an Penicillin-bindende Proteine ??(PBP), wodurch der letzte Transpeptidierungsschritt der Peptidoglycansynthese in bakteriellen Zellwänden gehemmt wird. Folge davon ist die Lyse von Bakterien durch autolytische Enzyme.

Sonstige Hinweise

Breitspektrum, dritte Generation Cephalosporin-Antibiotikum

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAB9060 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

Sicherheitshinweise

• Piktogramme: GHS08
• Signalwort: Danger
• H-Sätze: H317,H334
• P-Sätze: P261 - P280 - P284 - P304 + P340 - P333 + P313 - P342 + P311
• Gefahreneinstufungen: Resp. Sens. 1 - Skin Sens. 1
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable