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PHR1690

Supelco

Disulfiram

Pharmaceutical Secondary Standard; Certified Reference Material

Synonym(e):

Tetraethylthiuramdisulfid, Bis-(diethylthiocarbamoyl)-disulfid, Bis-(diethylthiocarbamyl)-disulfid, Disulfiram, TETD

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About This Item

Lineare Formel:
(C2H5)2NCSS2CSN(C2H5)2
CAS-Nummer:
Molekulargewicht:
296.54
Beilstein:
1712560
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
pharmaceutical secondary standard

Qualitätsniveau

Agentur

traceable to BP 132
traceable to Ph. Eur. D2950000
traceable to USP 1224008

API-Familie

disulfiram

Analysenzertifikat (CofA)

current certificate can be downloaded

Verpackung

pkg of 1 g

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

69-71 °C (lit.)

Anwendung(en)

pharmaceutical (small molecule)

Format

neat

Lagertemp.

2-30°C

SMILES String

CCN(CC)C(=S)SSC(=S)N(CC)CC

InChI

1S/C10H20N2S4/c1-5-11(6-2)9(13)15-16-10(14)12(7-3)8-4/h5-8H2,1-4H3

InChIKey

AUZONCFQVSMFAP-UHFFFAOYSA-N

Angaben zum Gen

human ... ALDH2(217)

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Allgemeine Beschreibung

Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Disulfiram is clinically used in the treatment of chronic alcoholism.

Anwendung

Alkoholdehydrogenase-Inhibitor
Disulfiram may be used as a pharmaceutical reference standard for the determination of the analyte in biological fluids and pharmaceutical formulations by high performance liquid chromatography and spectrophotometry, respectively.
These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.

Hinweis zur Analyse

These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available.

Sonstige Hinweise

This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.

Fußnote

To see an example of a Certificate of Analysis for this material enter LRAC2079 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.

Empfohlene Produkte

Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial.

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Gefahreneinstufungen

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Skin Sens. 1 - STOT RE 2

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

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Kunden haben sich ebenfalls angesehen

Simultaneous determination of disulfiram and two of its dithiocarbamate metabolites in human plasma by reversed-phase liquid chromatography
Masso PD, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 224(3), 457-464 (1981)
Determination of disulfiram and metabolites from biological fluids by high-performance liquid chromatography
Jensen JC, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 181(3-4), 407-416 (1980)
Spectrophotometric determination of methimazole, D-penicillamine, captopril, and disulfiram in pure form and drug formulations
Skowron M and Ciesielski W
Journal of Analytical Chemistry, 66(8), 714-719 (2011)

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