C5149

Kalzium-Ionophor A23187 gemischtes Calcium-Magnesiumsalz

Approximate 1:1 molar ratio Ca:Mg. Actual content given on label.

• Synonym(e): Calcimycin, Calcium-Ionophor gemischtes Calcium-Magnesiumsalz
• Empirische Formel (Hill-System): C₂₉H₃₇N₃O₆
• Molekulargewicht: 523.62
• MDL-Nummer: MFCD00213962
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24892759
• NACRES: NA.47

Eigenschaften

• Qualitätsniveau: 200
• Assay: 99% (TLC)
• Form: powder
• Löslichkeit: chloroform/methanol: 10 mg/mL, clear, faintly yellow
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: 2-8°C
• SMILES String: [Mg++].[Ca++].CNc1ccc2oc(CC3OC4(CCC3C)OC(C(C)CC4C)C(C)C(=O)c5ccc[nH]5)nc2c1C(O)=O
• InChI: 1S/C29H37N3O6.Ca.Mg/c1-15-10-11-29(17(3)13-16(2)27(38-29)18(4)26(33)20-7-6-12-31-20)37-22(15)14-23-32-25-21(36-23)9-8-19(30-5)24(25)28(34)35;;/h6-9,12,15-18,22,27,30-31H,10-11,13-14H2,1-5H3,(H,34,35);;/q;2*+2
• InChIKey: HKVXGTQLKZNXPV-UHFFFAOYSA-N

Beschreibung

Anwendung

Calcium Ionophore A23187 mixed calcium magnesium salt has been used as a calcium ionophore to increase the intracellular levels of calcium.

Ionophore highly selective for Ca²⁺. Potentiates responses to NMDA but not to quisqualate. In cell culture, stimulates nitric oxide production by calmodulin-dependent constitutive nitric oxide synthase.

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302 + H312 + H332,H315,H319,H335
• P-Sätze: P261 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Zielorgane: Respiratory system
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable