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N-Propionylglycin
analytical standard
Synonym(e):
2-(Propionylamino)-essigsäure, N-(1-Oxopropyl)-glycin, NSC 158539, Propionylglycin
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About This Item
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Qualität
analytical standard
Qualitätsniveau
Assay
≥98.0% (HPLC)
Haltbarkeit
limited shelf life, expiry date on the label
Anwendung(en)
clinical testing
Format
neat
Lagertemp.
2-8°C
SMILES String
OC(CNC(CC)=O)=O
InChI
1S/C5H9NO3/c1-2-4(7)6-3-5(8)9/h2-3H2,1H3,(H,6,7)(H,8,9)
InChIKey
WOMAZEJKVZLLFE-UHFFFAOYSA-N
Verwandte Kategorien
Biochem./physiol. Wirkung
Propionylglycine is an acyl glycine. Acyl glycines are normally minor metabolites of fatty acids. However, the excretion of certain acyl glycines is increased in several inborn errors of metabolism. In certain cases the measurement of these metabolites in body fluids can be used to diagnose disorders associated with mitochondrial fatty acid beta-oxidation. Acyl glycines are produced through the action of glycine N-acyltransferase (EC 2.3.1.13) which is an enzyme that catalyzes the chemical reaction:acyl-CoA + glycine < -- > CoA + N-acylglycine. The level of propionylglycine is elevated in patients with propionic acidemia, which is an inherited deficiency of propionyl-CoA carboxylase.
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Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
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