90970

γ-Butyrolacton

analytical standard

• Synonym(e): γ-Hydroxybuttersäure-Lacton, 4-Butyrolacton, GBL
• Empirische Formel (Hill-System): C₄H₆O₂
• CAS-Nummer: 96-48-0
• Molekulargewicht: 86.09
• Beilstein: 105248
• EG-Nummer: 202-509-5
• MDL-Nummer: MFCD00005386
• UNSPSC-Code: 85151701
• PubChem Substanz-ID: 329769980
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Dampfdichte: 3 (vs air)
• Dampfdruck: 1.5 mmHg ( 20 °C)
• Assay: ≥99.0% (GC)
• Selbstzündungstemp.: 851 °F
• Haltbarkeit: limited shelf life, expiry date on the label
• Expl.-Gr.: 16 %
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Verunreinigungen: ≤0.3% water
• Brechungsindex: n20/D 1.436 (lit.)
• bp: 204-205 °C (lit.)
• mp (Schmelzpunkt): −45 °C (lit.)
• Dichte: 1.12 g/mL at 25 °C (lit.)
• Anwendung(en): cleaning products; cosmetics; flavors and fragrances; food and beverages; personal care
• Format: neat
• Lagertemp.: 2-8°C
• SMILES String: O=C1CCCO1
• InChI: 1S/C4H6O2/c5-4-2-1-3-6-4/h1-3H2
• InChIKey: YEJRWHAVMIAJKC-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

γ-Butyrolactone (GBL) is a related lactone analog of γ-hydroxybutyric acid (GHB), a widespread drug of abuse, identified as an endogenous constituent of the mammalian brain, in which it exhibits a strong central nervous system depressant effect. GBL is considered as a legal substitute of GHB, and commonly identified in beverages including coffee, apple cider vinegar, tea, carbonated drinks, etc.

Anwendung

γ-Butyrolactone may be used as an analytical reference standard for the quantification of the analyte in roasted Italian chestnuts, wine samples, beverages using chromatography techniques.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

Vorstufe von γ-Hydroxybuttersäure (GHB). Es blockiert die Freisetzung von Dopamin durch die Hemmung der Impulsleitung in dopaminergen Neuronen. Die Vorbehandlung mit γ-Butyrolacton ermöglicht den Nachweis einer autorezeptorvermittelten Dopaminausschüttung.

Sicherheitshinweise

• Piktogramme: GHS05,GHS07
• Signalwort: Danger
• H-Sätze: H302,H318,H336
• P-Sätze: P261 - P264 - P271 - P280 - P301 + P312 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 4 Oral - Eye Dam. 1 - STOT SE 3
• Zielorgane: Central nervous system
• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): 208.4 °F - closed cup
• Flammpunkt (°C): 98 °C - closed cup