90240

Glycerintriacetat

≥99.0% (GC)

• Synonym(e): 1,2,3-Triacetoxy-propan, 1,2,3-Triacetylglycerin, Triacetin
• Lineare Formel: (CH₃COOCH₂)₂CHOCOCH₃
• CAS-Nummer: 102-76-1
• Molekulargewicht: 218.20
• Beilstein: 1792353
• EG-Nummer: 203-051-9
• MDL-Nummer: MFCD00008716
• UNSPSC-Code: 12352211
• PubChem Substanz-ID: 329769862
• NACRES: NA.25

Eigenschaften

• Qualitätsniveau: 200
• Assay: ≥99.0% (GC)
• Form: liquid
• Brechungsindex: n20/D 1.431
• bp: 258-260 °C (lit.)
• Dichte: 1.158 g/mL at 20 °C
• Lipid-Typ: saturated FAs
• SMILES String: CC(=O)OCC(COC(C)=O)OC(C)=O
• InChI: 1S/C9H14O6/c1-6(10)13-4-9(15-8(3)12)5-14-7(2)11/h9H,4-5H2,1-3H3
• InChIKey: URAYPUMNDPQOKB-UHFFFAOYSA-N

Beschreibung

Anwendung

• Epigenetic priming targets tumor heterogeneity to shift transcriptomic phenotype of pancreatic ductal adenocarcinoma towards a Vitamin D susceptible state.: This groundbreaking study utilizes glyceryl triacetate as part of an epigenetic priming strategy to sensitize pancreatic ductal adenocarcinoma to Vitamin D, marking a significant advancement in cancer treatment modalities (He et al., 2024).


• Glyceryl triacetate promotes blood-brain barrier recovery after ischemic stroke through lipogenesis-mediated IL-33 in mice.: Research demonstrates glyceryl triacetate′s effectiveness in enhancing blood-brain barrier repair post-ischemic stroke via lipogenesis pathways, offering insights into novel stroke recovery treatments (Wei et al., 2023).


• Development of A Nanostructured Lipid Carrier-Based Drug Delivery Strategy for Apigenin: Experimental Design Based on CCD-RSM and Evaluation against NSCLC In Vitro.: This study details the formulation of a nanostructured lipid carrier incorporating glyceryl triacetate, optimized for delivering apigenin to combat non-small cell lung cancer, emphasizing the potential of glyceryl triacetate in targeted therapy applications (Wang et al., 2023).


• Are New Phthalate Ester Substitutes Safer than Traditional DBP and DiBP Comparative Endocrine-Disrupting Analyses on Zebrafish Using In Vivo, Transcriptome, and In Silico Approaches.: Investigating glyceryl triacetate as a safer alternative to traditional phthalate esters, this study explores its lower endocrine-disrupting effects, contributing to safer industrial and pharmaceutical applications (Tan et al., 2023).


• Glyceryl triacetate feeding in mice increases plasma acetate levels but has no anticonvulsant effects in acute electrical seizure models.: This research evaluates the biochemical impact of glyceryl triacetate on plasma acetate levels, providing valuable data on its metabolic effects despite a lack of anticonvulsant properties in specific seizure models (Xu et al., 2022).

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 1
• Flammpunkt (°F): 298.4 °F - closed cup
• Flammpunkt (°C): 148 °C - closed cup
• Persönliche Schutzausrüstung: Eyeshields, Gloves