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Merck

69311

Supelco

Chinin

certified reference material, TraceCERT®, Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Synonym(e):

6′-Methoxycinchonidin

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About This Item

Empirische Formel (Hill-System):
C20H24N2O2
CAS-Nummer:
Molekulargewicht:
324.42
Beilstein:
91867
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
41116107
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

certified reference material
TraceCERT®

Qualitätsniveau

Produktlinie

TraceCERT®

Haltbarkeit

limited shelf life, expiry date on the label

Hersteller/Markenname

Manufactured by: Sigma-Aldrich Production GmbH, Switzerland

Lagerbedingungen

under inert gas

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

mp (Schmelzpunkt)

173-175 °C (lit.)

Anwendung(en)

food and beverages

Format

neat

SMILES String

COc1ccc2nccc([C@@H](O)[C@@H]3C[C@@H]4CCN3C[C@@H]4C=C)c2c1

InChI

1S/C20H24N2O2/c1-3-13-12-22-9-7-14(13)10-19(22)20(23)16-6-8-21-18-5-4-15(24-2)11-17(16)18/h3-6,8,11,13-14,19-20,23H,1,7,9-10,12H2,2H3/t13-,14-,19-,20+/m0/s1

InChIKey

LOUPRKONTZGTKE-WZBLMQSHSA-N

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Allgemeine Beschreibung

This certified reference material (CRM) is produced and certified in accordance with ISO/IEC 17025 and ISO 17034. This CRM is traceable to primary material from an NMI, e.g. NIST or NMIJ.
Certified content by quantitative NMR incl. uncertainty and expiry date are given on the certificate.
Download your certificate at: http://www.sigma-aldrich.com.

Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem./physiol. Wirkung

blockiert Kaliumkanäle

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Vorsicht

Store under argon.

Rechtliche Hinweise

TraceCERT is a registered trademark of Merck KGaA, Darmstadt, Germany

Piktogramme

Exclamation mark

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Acute Tox. 4 Oral - Skin Sens. 1

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 1


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Xiong-Li Liu et al.
Organic letters, 15(6), 1246-1249 (2013-03-05)
A wide range of structurally diverse 3,3'-thiopyrrolidonyl spirooxindoles bearing three contiguous stereogenic centers can be smoothly obtained via a domino Michael/cyclization reaction between 3-isothiocyanato oxindoles and 3-methyl-4-nitro-5-alkenyl-isoxazoles with commercially available quinine as the catalyst under mild conditions. The protocol is
George Praygod et al.
Malaria journal, 7, 210-210 (2008-10-22)
The efficacy of intravenous quinine, which is the mainstay for treating severe malaria in children, is decreasing in South East Asia and Africa. Artemisinin derivatives are a potential alternative to quinine. However, their efficacy compared to quinine in treating severe
Jane Achan et al.
Malaria journal, 10, 144-144 (2011-05-26)
Quinine remains an important anti-malarial drug almost 400 years after its effectiveness was first documented. However, its continued use is challenged by its poor tolerability, poor compliance with complex dosing regimens, and the availability of more efficacious anti-malarial drugs. This
Hmwe Hmwe Kyu et al.
Bulletin of the World Health Organization, 87(12), 896-904 (2010-05-11)
To summarize the existing evidence on the efficacy of artemether and arteether, two artemisinin derivatives, versus quinine for treating cerebral malaria in children. We searched the Cochrane Central Register of Controlled Trials, MEDLINE, EMBASE and the http://clinicaltrials.gov web site. We
Annemarie R Kreeftmeijer-Vegter et al.
Malaria journal, 12, 115-115 (2013-03-30)
Exchange transfusion (ET) has remained a controversial adjunct therapy for the treatment of severe malaria. In order to assess the relative contribution of ET to parasite clearance in severe malaria, all patients receiving ET as an adjunct treatment to parenteral

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