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Merck

68612

Supelco

Bakuchiol

analytical standard

Synonym(e):

(S)-Bakuchiol, 4-[(1E,3S)-3-Ethenyl-3,7-dimethyl-1,6-octadien-1-yl]-phenol

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About This Item

Empirische Formel (Hill-System):
C18H24O
CAS-Nummer:
Molekulargewicht:
256.38
Beilstein:
3611720
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:
NACRES:
NA.24

Qualität

analytical standard

Qualitätsniveau

Assay

≥95.0% (HPLC)

Optische Aktivität

[α]/D +24.0 to +30.0°, c = 0.1 in chloroform

Haltbarkeit

limited shelf life, expiry date on the label

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

food and beverages

Format

neat

Lagertemp.

−20°C

SMILES String

C\C(C)=C/CC[C@@](C)(C=C)\C=C\c1ccc(O)cc1

InChI

1S/C18H24O/c1-5-18(4,13-6-7-15(2)3)14-12-16-8-10-17(19)11-9-16/h5,7-12,14,19H,1,6,13H2,2-4H3/b14-12+/t18-/m1/s1

InChIKey

LFYJSSARVMHQJB-QIXNEVBVSA-N

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Anwendung

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Piktogramme

Environment

Signalwort

Warning

H-Sätze

Gefahreneinstufungen

Aquatic Acute 1 - Aquatic Chronic 1

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 3

Flammpunkt (°F)

363.2 °F - Pensky-Martens closed cup

Flammpunkt (°C)

184 °C - Pensky-Martens closed cup


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Die Dokumentenbibliothek aufrufen

Sun-Hye Lim et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(5), 425-430 (2011-03-09)
Estrogenic activities of ethanol extract and its active components from Psoralea corylifolia L. were studied using various in vitro assays. The main components from ethanol extract were analyzed to be bakuchiol, psoralen, isobavachalcone, isobavachromene, and bavachinin. In a fractionation procedure
P-J Hsu et al.
Natural product research, 23(8), 781-788 (2009-05-07)
Bioactivity guided fractionation of an EtOAc extract from Psoralidium tenuiflorum (Pursh) Rydb. (family : Fabaceae) yielded the known compound bakuchiol as a racemic mixture. This compound was purified by liquid-liquid partitioning and chromatography followed by NMR and GCMS characterisation. This
Gang Zhao et al.
Biochemical pharmacology, 75(9), 1835-1847 (2008-03-11)
Monoamine transporters play key roles in controlling monoamine levels and modulating monoamine reuptake. The objective of the present study was to identify monoamine transporter inhibitors from herbal sources. We discovered that bakuchiol analogs isolated from Fructus Psoraleae inhibited monoamine transporter
Hong-li Chen et al.
Yao xue xue bao = Acta pharmaceutica Sinica, 45(4), 467-470 (2011-03-02)
The in vitro antitumor activity of bakuchiol was exploited, compared with tamoxifen. The result of biological activities showed that bakuchiol could inhibit human breast cancer and the IC50 values were 2.89 x 10(-5) mol L(-1) and 8.29 x 10(-3) mol
Hongli Chen et al.
Bioorganic & medicinal chemistry, 16(5), 2403-2411 (2007-12-08)
A series of derivatives of bakuchiol were synthesized and tested in vitro for their cytotoxicity, and inhibition of T cell proliferation and B cell proliferation. The data obtained provided preliminary structure-activity relationships of the compounds as immunosuppressive activity.

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