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Merck

60634

Sigma-Aldrich

Katalase aus Micrococcus lysodeikticus

solution, dark brown

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About This Item

CAS-Nummer:
MDL-Nummer:
UNSPSC-Code:
12352204
NACRES:
NA.54

Biologische Quelle

bacterial (Micrococcus lysodeikticus)

Qualitätsniveau

Form

solution

Spezifische Aktivität

65,000-150,000 U/mL

Mol-Gew.

Mr ~230000

Methode(n)

microbe id | metabolite detection: suitable

Farbe

dark brown

Löslichkeit

0.05 M phosphate buffer pH 7.0: soluble, clear, brown (1:10)

Protein-ID-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Lagertemp.

2-8°C

InChI

1S/C9H10O3/c1-2-12-9(11)7-3-5-8(10)6-4-7/h3-6,10H,2H2,1H3

InChIKey

NUVBSKCKDOMJSU-UHFFFAOYSA-N

Allgemeine Beschreibung

Research area: Cell Signaling

Catalase (CAT) is an antioxidant enzyme, encoded by the CAT gene family. The enzyme is ubiquitously expressed in most of the aerobic organisms.

Anwendung

Catalase from Micrococcus lysodeikticus has been used to eliminate excess of hydrogen peroxide production during sugar analog synthesis by in vitro biocatalytic cascade. It has also been used as a standard to evaluate oxidative stress by indirectly measuring catalytic activity.

Biochem./physiol. Wirkung

Catalase rapidly converts hydrogen peroxide to oxygen and water. It exhibits antioxidant activity and elicits a defense mechanism against reactive oxygen species (ROS). Catalase plays a role in neutralizing noxious hydrogen peroxide in nature as well as in various industries such as textile, pharma, and dairy. Micrococcus lysodeikticus catalase is a heme-containing protein.Catalase, along with various key cellular systems involved in hydrogen peroxide (H2O2) processing, plays a key role in regulating cellular redox balance and aids in cellular and intercellular signaling.

Einheitendefinition

1 U entspricht der Enzymmenge, die 1 μmol Wasserstoffperoxid pro Minute bei pH 7.0 und 25°C abbaut

Piktogramme

Health hazard

Signalwort

Danger

H-Sätze

Gefahreneinstufungen

Resp. Sens. 1

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves


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Hessam Sepasi Tehrani et al.
Progress in biophysics and molecular biology, 140, 5-12 (2018-03-14)
Catalase is one of the firsts in every realm of biological sciences. At the same time it also has a number of unusual features. It has one of the highest turnover numbers of all enzymes. It is essential for neutralizing
Pablo Burraco et al.
BMC evolutionary biology, 17(1), 164-164 (2017-07-08)
Adaptive plasticity is essential for many species to cope with environmental heterogeneity. In particular, developmental plasticity allows organisms with complex life cycles to adaptively adjust the timing of ontogenetic switch points. Size at and time to metamorphosis are reliable fitness
Ivan Gomez-Mestre et al.
PloS one, 8(12), e84266-e84266 (2013-12-21)
Many amphibian species exploit temporary or even ephemeral aquatic habitats for reproduction by maximising larval growth under benign conditions but accelerating development to rapidly undergo metamorphosis when at risk of desiccation from pond drying. Here we determine mechanisms enabling developmental
Margarita Florencio et al.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology, 242, 110654-110654 (2020-01-12)
Organisms are exposed to multiple environmental factors simultaneously to which they often respond behaviorally, morphologically and/or physiologically. Amphibian larvae are quite plastic and efficiently adjust their phenotype and physiology to the reigning local conditions. Here we tested whether the combination
An improved procedure using ferricyanide for detecting catalase isozymes.
W Woodbury et al.
Analytical biochemistry, 44(1), 301-305 (1971-11-01)

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