40733

trans-2-Tetradecenoyl-L-carnitin

analytical standard

• Synonym(e): (2R)-3-Carboxy-N,N,N-trimethyl-2-[[(2E)-1-oxo-2-tetradecen-1-yl]-oxy]-1-propanaminium Inneres Salz, trans-2-Myristenoyl-L-carnitin
• Empirische Formel (Hill-System): C₂₁H₃₉NO₄
• Molekulargewicht: 369.54
• UNSPSC-Code: 41116107
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Assay: ≥95.0% (LC/MS)
• Optische Aktivität: [α]/D -12±2°, c = 0.1 in methanol
• Haltbarkeit: limited shelf life, expiry date on the label
• Anwendung(en): clinical testing
• Format: neat
• Lagertemp.: −20°C
• SMILES String: [O-]C(C([H])([H])[C@](OC(/C([H])=C([H])/C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H])=O)([H])C([H])([H])[N+](C([H])([H])[H])(C([H])([H])[H])C([H])([H])[H])=O

Beschreibung

Allgemeine Beschreibung

trans-2-Tetradecenoyl-L-carnitine, belonging to the class of acylcarnitines, serves as a specific diagnostic metabolite biomarker, which increases in very long-chain acyl CoA dehydrogenase (VLCAD) deficiency, existing as a long-chain β-oxidation defect in newborns.

Anwendung

trans-2-Tetradecenoyl-L-carnitine may be used as an analytical reference standard in the following:

• Quantification of the analyte in biological samples using high-performance liquid chromatography coupled to tandem mass spectrometry (HPLC/MS/MS).
• Quantification of the analyte in dried blood spots using chip-based nanoelectrospray source coupled with high resolution mass spectrometry (chip-based nanoESI- HRMS) and targeted liquid chromatography-tandem mass spectrometry (LC/MS/MS).

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable