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Merck

35405

Supelco

α-Zearalanol -Lösung

~10 μg/mL in acetonitrile, analytical standard

Synonym(e):

(3S,7R)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-on -Lösung, 2,4-Dihydroxy-6-(6α,10-dihydroxyundecyl)-benzoesäure-μ-lacton -Lösung

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About This Item

Empirische Formel (Hill-System):
C18H26O5
CAS-Nummer:
Molekulargewicht:
322.40
EG-Nummer:
MDL-Nummer:
UNSPSC-Code:
85151701
PubChem Substanz-ID:

Qualität

analytical standard

Haltbarkeit

limited shelf life, expiry date on the label

Arzneimittelkontrolle

regulated under CDSA - not available from Sigma-Aldrich Canada

Verfügbarkeit

not available in Canada

Konzentration

~10 μg/mL in acetonitrile

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

Anwendung(en)

cleaning products
cosmetics
food and beverages
personal care

Format

single component solution

Lagertemp.

−20°C

SMILES String

C[C@H]1CCC[C@H](O)CCCCCc2cc(O)cc(O)c2C(=O)O1

InChI

1S/C18H26O5/c1-12-6-5-9-14(19)8-4-2-3-7-13-10-15(20)11-16(21)17(13)18(22)23-12/h10-12,14,19-21H,2-9H2,1H3/t12-,14+/m0/s1

InChIKey

DWTTZBARDOXEAM-GXTWGEPZSA-N

Allgemeine Beschreibung

α-Zearalanol is a resorcyclic acid lactone. It is a plant derived, nonsteroidal phytoestrogen, often used as a dietary supplement.

Anwendung

α-Zearalanol may be used as an analytical reference standard for the determination of the analyte in traditional Chinese medicines, human and animal urine by various chromatography techniques.
Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Hinweis zur Analyse

purity : ≥97.0% (HPLC)

Piktogramme

FlameExclamation mark

Signalwort

Danger

Gefahreneinstufungen

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Eye Irrit. 2 - Flam. Liq. 2

Lagerklassenschlüssel

3 - Flammable liquids

WGK

WGK 2

Flammpunkt (°F)

35.6 °F - closed cup

Flammpunkt (°C)

2.0 °C - closed cup


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Analysenzertifikate (COA)

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A rapid method for simultaneous determination of zearalenone, α-zearalenol, β-zearalenol, zearalanone, α-zearalanol and β-zearalanol in traditional Chinese medicines by ultra-high-performance liquid chromatography-tandem mass spectrometry.
Han Z, et al.
Journal of Chromatography. B, Biomedical Sciences and Applications, 879(5-6), 411-420 (2011)
Shaohui Zong et al.
Journal of bone and mineral metabolism, 30(2), 136-143 (2011-07-21)
To assess the ability of α-zearalanol (α-ZAL) to prevent bone loss in an ovariectomized (OVX) rat model of osteoporosis, α-ZAL was administered intragastrically to rats. After 35 days, the total body bone mineral density (BMD) was assessed in all rats. All
Marcella L Card et al.
Journal of agricultural and food chemistry, 60(6), 1480-1487 (2012-01-10)
Surface runoff from manure-fertilized fields is a significant source of endocrine-disrupting compounds (EDCs) in the environment. Sorption by soils may play a major role in the environmental fate of manure-borne EDCs, including 17α- and 17β-estradiol (17α-E2 and 17β-E2), estrone (E1)
Shen Qu et al.
Environmental science & technology, 46(24), 13202-13211 (2012-11-21)
Trenbolone acetate, melengestrol acetate, and zeranol are synthetic hormones extensively used as growth promoters in animal agriculture, yet despite occurrence in water and soil little is known about their environmental fate. Here, we establish the time scales and mechanisms by
A Pazaiti et al.
International journal of clinical practice, 66(1), 28-36 (2011-12-08)
Zearalenone (ZEN) is a non-steroidal mycoestrogen that widely contaminates agricultural products. ZEN and its derivatives share similar molecular mechanisms and activity with estrogens and interact with ERα and ERβ leading to changes in the reproductive system in both animals and

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