32496

1-Hydroxyibuprofen

VETRANAL^®, analytical standard

• Synonym(e): 2-[4-(1-Hydroxy-2-methyl-propyl)-phenyl]-propionsäure
• Empirische Formel (Hill-System): C₁₃H₁₈O₃
• CAS-Nummer: 53949-53-4
• Molekulargewicht: 222.28
• Beilstein: 22307543
• MDL-Nummer: MFCD08275586
• UNSPSC-Code: 41116107
• PubChem Substanz-ID: 329754248
• NACRES: NA.24

Eigenschaften

• Qualität: analytical standard
• Qualitätsniveau: 100
• Produktlinie: VETRANAL^®
• Haltbarkeit: limited shelf life, expiry date on the label
• Methode(n): HPLC: suitable; gas chromatography (GC): suitable
• Anwendung(en): forensics and toxicology; pharmaceutical (small molecule)
• Format: neat
• SMILES String: CC(C)C(O)c1ccc(cc1)C(C)C(O)=O
• InChI: 1S/C13H18O3/c1-8(2)12(14)11-6-4-10(5-7-11)9(3)13(15)16/h4-9,12,14H,1-3H3,(H,15,16)
• InChIKey: RMOQYHYFRKTDRI-UHFFFAOYSA-N

Beschreibung

Allgemeine Beschreibung

1-Hydroxyibuprofen is one of the metabolites of ibuprofen, which is classified under the non-steroidal anti-inflammatory drugs (NSAIDs) group of compounds.

Anwendung

1-Hydroxyibuprofen has been used as an analytical reference standard for the determination of the analyte in:

• Sewage sludge samples by QuEChERS (quick, easy, cheap, effective, rugged and safe) extraction with on-line solid-phase extract purification and pre-concentration, followed by analysis using liquid chromatography coupled to electrospray ionization-tandem mass spectrometry (LC-ESI-MS/MS) operating in multiple reaction monitoring (MRM) mode of detection.

It may be used as an analytical reference standard for the determination of the analyte in:

• Human urine samples by ultrasound-assisted emulsification microextraction (USAEME) and ultra-high performance liquid chromatography (UHPLC) with (ESI-MS/MS) with (MRM) detection.
• Wastewater samples by hollow fiber liquid phase microextraction (HF-LPME) followed by LC-ESI-MS/MS.

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Rechtliche Hinweise

VETRANAL is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• H-Sätze: H302
• P-Sätze: P264 - P270 - P301 + P312 - P501
• Gefahreneinstufungen: Acute Tox. 4 Oral
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3