125660

Leucomalachitgrün

powder

• Synonym(e): 4,4′-Benzyliden-bis-(N,N-dimethylanilin)
• Lineare Formel: C₆H₅CH[C₆H₄N(CH₃)₂]₂
• CAS-Nummer: 129-73-7
• Molekulargewicht: 330.47
• Beilstein: 2140506
• EG-Nummer: 204-961-9
• MDL-Nummer: MFCD00008315
• UNSPSC-Code: 12171500
• PubChem Substanz-ID: 24847677
• NACRES: NA.47

Eigenschaften

• Form: powder
• Qualitätsniveau: 100
• mp (Schmelzpunkt): 100-102 °C (lit.)
• λmax: 623 nm
• Anwendung(en): diagnostic assay manufacturing; hematology; histology
• Lagertemp.: room temp
• SMILES String: CN(C)c1ccc(cc1)C(c2ccccc2)c3ccc(cc3)N(C)C
• InChI: 1S/C23H26N2/c1-24(2)21-14-10-19(11-15-21)23(18-8-6-5-7-9-18)20-12-16-22(17-13-20)25(3)4/h5-17,23H,1-4H3
• InChIKey: WZKXBGJNNCGHIC-UHFFFAOYSA-N

Beschreibung

Anwendung

Leucomalachite green has been used as a reagent in presumptive tests which are used to detect invisible blood stains.

Biochem./physiol. Wirkung

Leucomalachite green (LMG) is a chief metabolite of malachite green, a triphenylmethane dye that has been used generally as an antifungal drug in the fish industry. DNA adducts formed in livers of rats fed with leucomalachite green have been observed with little mutagenic or carcinogenic effect. LMG is one of the most commonly used reagents for presumptive blood test. It gives a characteristic green color in the presence of blood. LMG destroys DNA in the blood, therefore, the chances of DNA recovery and amplification is reduced or eliminated.

Sicherheitshinweise

• Piktogramme: GHS08,GHS07,GHS09
• Signalwort: Warning
• H-Sätze: H302,H341,H351,H410
• P-Sätze: P202 - P264 - P273 - P280 - P301 + P312 - P308 + P313
• Gefahreneinstufungen: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Carc. 2 - Muta. 2
• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: dust mask type N95 (US), Eyeshields, Gloves