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Harpagosid

Name: Harpagosid
Brand: SIAL

primary reference standard

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About This Item

Empirische Formel (Hill-System):

C₂₄H₃₀O₁₁

CAS-Nummer:

19210-12-9

Molekulargewicht:

494.49

EG-Nummer:

242-881-6

MDL-Nummer:

MFCD00017415

UNSPSC-Code:

85151701

PubChem Substanz-ID:

329747071

NACRES:

NA.24

Qualität

primary reference standard

Haltbarkeit

limited shelf life, expiry date on the label

Hersteller/Markenname

HWI

Methode(n)

HPLC: suitable
gas chromatography (GC): suitable

SMILES String

C[C@@]1(C[C@@H](O)[C@]2(O)C=CO[C@@H](O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)[C@H]12)OC(=O)\C=C\c4ccccc4

InChI

1S/C24H30O11/c1-23(35-16(27)8-7-13-5-3-2-4-6-13)11-15(26)24(31)9-10-32-22(20(23)24)34-21-19(30)18(29)17(28)14(12-25)33-21/h2-10,14-15,17-22,25-26,28-31H,11-12H2,1H3/b8-7+/t14-,15-,17-,18+,19-,20-,21+,22+,23+,24-/m1/s1

InChIKey

KVRQGMOSZKPBNS-FMHLWDFHSA-N

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Allgemeine Beschreibung

Produced and qualified by HWI pharma services GmbH.
Exact content by quantitative NMR can be found on the certificate.

Anwendung

Referenzstandard für die Analyse von pflanzlichen Medizinprodukten.

Piktogramme

GHS07

Signalwort

Warning

H-Sätze

H302

P-Sätze

P264 - P270 - P301 + P312 - P501

Gefahreneinstufungen

Acute Tox. 4 Oral

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

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Analysenzertifikate (COA)

Lot/Batch Number

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Validated HPTLC methods for the determination of salicin in Salix sp. and of harpagoside in Harpagophytum [corrected] procumbens.

Steffen Wagner et al.

Journal of pharmaceutical and biomedical analysis, 48(3), 587-591 (2008-07-08)

Preparations of Harpagophytum procumbens and of Salix species are successfully used for the treatment of degenerative rheumatism and painful arthrosis. For the quality control of both drugs, rapid methods of quantification are desirable. Here we report the development of two

Harpagoside attenuates MPTP/MPP⁺ induced dopaminergic neurodegeneration and movement disorder via elevating glial cell line-derived neurotrophic factor.

Xiaoyu Sun et al.

Journal of neurochemistry, 120(6), 1072-1083 (2011-12-24)

Parkinson's disease is a chronic neurodegenerative movement disorder characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta. New therapeutic approaches aiming at delaying or reversing the neurodegenerative process are under active investigations. In this work, we

Cognitive-enhancing and antioxidant activities of iridoid glycosides from Scrophularia buergeriana in scopolamine-treated mice.

Eun Ju Jeong et al.

European journal of pharmacology, 588(1), 78-84 (2008-05-09)

The cognitive-enhancing activities of E-harpagoside and 8-O-E-p-methoxycinnamoylharpagide (MCA-Hg) isolated from Scrophularia buergeriana were evaluated in scopolamine-induced amnesic mice by the Morris water maze and by passive avoidance tests. E-harpagoside and MCA-Hg significantly improved the impairment of reference memory induced by

Optimization of solid-phase extraction for the liquid chromatography-mass spectrometry analysis of harpagoside, 8-para-coumaroyl harpagide, and harpagide in equine plasma and urine.

Cyril Colas et al.

Journal of chromatographic science, 46(2), 174-183 (2008-03-28)

Solid-phase extraction cartridges among those usually used for screening in horse doping analyses are tested to optimize the extraction of harpagoside (HS), harpagide (HG), and 8-para-coumaroyl harpagide (8PCHG) from plasma and urine. Extracts are analyzed by liquid chromatography coupled with

Preparative isolation and purification of harpagoside from Scrophularia ningpoensis hemsley by high-speed counter-current chromatography.

Shengqiang Tong et al.

Phytochemical analysis : PCA, 17(6), 406-408 (2006-12-06)

The bioactive component harpagoside was successfully separated from the crude extract of Scrophularia ningpoensis Hemsley by one-step purification using high-speed counter-current chromatography (HSCCC). A two-phase solvent system containing n-butanol:ethyl acetate:water (1:9:10) was selected following consideration of the partition coefficient of

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Dokumente

Harpagosid

primary reference standard

About This Item

Eigenschaften

Qualität

Haltbarkeit

Hersteller/Markenname

Methode(n)

SMILES String

InChI

InChIKey

Beschreibung

Allgemeine Beschreibung

Anwendung

Sicherheitshinweise

Piktogramme

Signalwort

H-Sätze

P-Sätze

Gefahreneinstufungen

Lagerklassenschlüssel

WGK

Flammpunkt (°F)

Flammpunkt (°C)

Dokumentation

Analysenzertifikate (COA)

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Peer-Reviewed-Artikel

Technischer Dienst