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Merck

MAB5778

Sigma-Aldrich

Anti-NMDAR2B Antibody, CT

ascites fluid, clone 1C6.5C4, Chemicon®

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

ascites fluid

Klon

1C6.5C4, monoclonal

Speziesreaktivität

human, rat, rabbit, mouse

Hersteller/Markenname

Chemicon®

Methode(n)

western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Spezifität

NMDAR2B, C-terminal. By Western blot the antibody reacts with a band at ~170 kDa on rat brain lysate.

Immunogen

Recombinant protein from rat NMDAR2B.

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurotransmitter & Rezeptoren
This Anti-NMDAR2B Antibody, C-terminal is validated for use in WB for the detection of NMDAR2B.
Western blot: 1:100-1:1,000 on rat brain lysate.

Optimal working dilutions must be determined by end user.

Physikalische Form

Ascites
Liquid ascites.

Lagerung und Haltbarkeit

6 months at -20°C from date of shipment

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Empfehlung

Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

GluN2B protein deficits in the left, but not the right, hippocampus in schizophrenia.
Geddes, AE; Huang, XF; Newell, KA
BMC Psychiatry null
Marie Lise Frandemiche et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(17), 6084-6097 (2014-04-25)
Tau is a microtubule-associated protein well known for its stabilization of microtubules in axons. Recently, it has emerged that tau participates in synaptic function as part of the molecular pathway leading to amyloid-beta (Aβ)-driven synaptotoxicity in the context of Alzheimer's
Matthew T Swulius et al.
The Journal of comparative neurology, 518(20), 4243-4260 (2010-09-30)
In this study, we used electron tomography as well as immunogold labeling to analyze the morphology and distribution of proteins within postsynaptic densities (PSDs) isolated from rats before birth (embryonic day 19) and at postnatal days 2, 21, and 60.
Wenhui Qu et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 40(50), 9552-9563 (2020-11-04)
Triggering receptor expressed on myeloid cells 2 (TREM2), a receptor exclusively expressed by microglia in the brain, modulates microglial immune homeostasis. Human genetic studies have shown that the loss-of-function mutations in TREM2 signaling are strongly associated with an elevated risk
D J Laurie et al.
Brain research. Molecular brain research, 51(1-2), 23-32 (1998-01-14)
Mouse monoclonal antibodies were raised against bacterially expressed protein sequences of the NR2A, NR2B, NR2C and NR2D subunits of the rat NMDA receptor. From immunoblots of rat brain proteins, the apparent molecular weights of these subunits were 165, 170, 135

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