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Key Documents

MAB5204

Sigma-Aldrich

Anti-Agrin Antibody

Chemicon®, from mouse

Synonym(e):

Anti-AGRIN, Anti-CMSPPD

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

monoclonal

Speziesreaktivität

mouse, rat

Hersteller/Markenname

Chemicon®

Methode(n)

immunocytochemistry: suitable
western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... AGRN(375790)

Spezifität

MAB5204 recognizes rat and mouse agrin. The epitope has been mapped near the splicing site Z. Binding of this antibody to agrin causes marked reduction in nAChR clusters.

Immunogen

Recombinant rat agrin (C-terminal construct)

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Wachstumskegel & Axonlenkung

Synapsen & Synapsenbiologie
Anti-Agrin Antibody is an antibody against Agrin for use in WB & IC.
Immunocytochemistry: 10 μg/mL

Optimal working dilutions must be determined by the end user.

Physikalische Form

Format: Purified
Purified immunoglobulin. Liquid in PBS containing 50% glycerol and 0.09% sodium azide.

Lagerung und Haltbarkeit

Maintain lyophilized at material -20°C or below for up to 12 months. After reconstitution maintain at -20°C to -70°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

The COOH-terminal domain of agrin signals via a synaptic receptor in central nervous system neurons.
Hoover, CL; Hilgenberg, LG; Smith, MA
The Journal of cell biology null
Jinping Zhang et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 20(1), 50-58 (2006-01-06)
It is well established that agrin, an extracellular matrix protein, plays a crucial role in the formation of neuromuscular junctions. Recent evidence indicates that agrin also contributes to immunological synapse formation. However, little is known about how agrin induces the
Hisashi Narai et al.
Neurology international, 1(1), e16-e16 (2009-01-01)
The transgenic animals with mutant copper/zinc superoxide dismutase (SOD1) DNA develop paralytic motor neuron disease resembling human amyotrophic lateral sclerosis (ALS) patients and are commonly used as models for ALS. In the transgenic (Tg) mice with the G93A mutation of
Syndecan-4 is associated with beta-cells in the pancreas and the MIN6 beta-cell line.
Jennifer Y C Cheng,John Whitelock,Laura Poole-Warren
Histochemistry and Cell Biology null
Nandor Nagy et al.
Development (Cambridge, England), 145(9) (2018-04-22)
The enteric nervous system (ENS) arises from neural crest cells that migrate, proliferate, and differentiate into enteric neurons and glia within the intestinal wall. Many extracellular matrix (ECM) components are present in the embryonic gut, but their role in regulating

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