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Key Documents

MAB1273C3

Sigma-Aldrich

Anti-Mitochondria Antibody, clone 113-1, Cy3 Conjugate

clone 113-1, from mouse, CY3 conjugate

Synonym(e):

Human Mitochondria

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

Konjugat

CY3 conjugate

Antikörperform

purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

113-1, monoclonal

Speziesreaktivität

human (mitochondria protein)

Darf nicht reagieren mit

rat (mitochondria protein), mouse (mitochondria protein)

Methode(n)

immunocytochemistry: suitable

Isotyp

IgG1

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Allgemeine Beschreibung

This antibody recognizes a 60 kDa nonglycosylated protein component of mitochondria found in human cells. It can be used to stain mitochondria in cell, tissue or biochemical preparations and can be used as a marker of the mitochondria in subcellular fractions. MAB1273C3 recognizes a 65 kD protein by immunoprecipitation and produces the stringy, "spaghetti-like", staining patten in the cytoplasm of human cells.

Spezifität

This antibody recognizes human. Antibody is not reactive with mouse or rodent.

Immunogen

Surface of intact human mitochondria

Anwendung

Research Category
Stammzellforschung

Zellstruktur
Research Sub Category
Entwicklungsneurowissenschaft

Organell- & Zellmarker
Detect Mitochondrial Marker using this mouse monoclonal antibody, Anti-Mitochondria Antibody, clone 113-1 & Cy3 Conjugate validated for use in ICC.
Evaluated by Immunocytochemistry in human adipose mesenchymal stem cells (SCC038).
Immunocytochemsitry Analysis: A 1:50 dilution of this antibody detected mitrochondria in human adipose mesenchymal stem cells (SCC038).

Qualität

Evaluated by Immunocytochemistry in neonatal human fibroblasts cells (SCC058).
Immunocytochemsitry Analysis: A 1:50 dilution of this antibody detected mitrochondria in neonatal human fibroblast cells (SCC058).

Zielbeschreibung

60 kDa calculated

Physikalische Form

Protein G Purified
Purified mouse monoclonal IgG1 conjugated to Cy3 in PBS with 0.1% sodium azide and 15mg/ml BSA.

Lagerung und Haltbarkeit

Maintain refrigerated at 2-8ºC protected from light in undiluted aliquots for up to 6 months from date of receipt.

Hinweis zur Analyse

Control
Neonatal human fibroblasts cells (SCC058).

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Roza K Przanowska et al.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 34(6), 7687-7702 (2020-04-12)
miR-206, miR-1a-1, and miR-1a-2 are induced during differentiation of skeletal myoblasts and promote myogenesis in vitro. miR-206 is required for skeletal muscle regeneration in vivo. Although this miRNA family is hypothesized to play an essential role in differentiation, a triple

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