GF334
IL-22,
Human Recombinant Animal Free
Synonym(e):
Interleukin-22, IL22
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About This Item
UNSPSC-Code:
12352202
eCl@ss:
32160405
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Allgemeine Beschreibung
IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share partial homology in their amino acid sequences, but they are dissimilar in their biological functions. Produced by T lymphocytes, IL-22 inhibits IL-4 production by Th2 cells, and induces acute phase reactants in the liver and pancreas. IL-22 signals through a receptor system consisting of IL-10Rβ/CRF2-4 and IL-22R, both of which are members of the class II cytokine-receptor family.
Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked
homodimeric protein containing of two 147 amino acid polypeptide chains.
Recombinant human IL-22 is a 33.6 kDa non-disulfide-linked
homodimeric protein containing of two 147 amino acid polypeptide chains.
Product Source: Protein is expressed in E.coli.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
The protein is manufactured without the use of any animal products/reagents and is considered Animal-Free and can be used in protocols where possible transmisson of animal viruses and contamination must be avoided.
Anwendung
Research Category
Stammzellforschung
Stammzellforschung
Research Sub Category
Wachstumsfaktoren & -rezeptoren
Wachstumsfaktoren & -rezeptoren
Qualität
Determined by its ability to induce IL-10 secretion in COLO 205 (human colon carcinoma cells). The expected ED50 for this effect is 0.7- 1.0ng/ml.
Physikalische Form
Product is presented in 10 mM NaCitrate, pH 4.0 and is filtered through a 0.2 micron filter before lyophilization.
Lagerung und Haltbarkeit
Store at -20°C for up to 4 months from date of receipt Centrifuge the vial prior to opening.
Reconstitute in water to a concentration of 0.5-1.0mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Reconstitute in water to a concentration of 0.5-1.0mg/ml. Do not vortex. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein and store in working aliquots at -20°C.
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
Signalwort
Warning
H-Sätze
Gefahreneinstufungen
Eye Irrit. 2 - STOT SE 3
Zielorgane
Respiratory system
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 1
Analysenzertifikate (COA)
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