FCMAB188F

Milli-Mark^® Anti-CD24-FITC Antibody, clone SN3

clone SN3, Milli-Mark^®, from mouse

• Synonym(e): Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

Eigenschaften

• Biologische Quelle: mouse
• Qualitätsniveau: 100
• Konjugat: FITC conjugate
• Antikörperform: purified immunoglobulin
• Antikörper-Produkttyp: primary antibodies
• Klon: SN3, monoclonal
• Speziesreaktivität: human
• Hersteller/Markenname: Milli-Mark^®
• Methode(n): flow cytometry: suitable
• Isotyp: IgG1κ
• NCBI-Hinterlegungsnummer: NP_037362.1
• UniProt-Hinterlegungsnummer: P25063
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... CD24(100133941)

Beschreibung

Allgemeine Beschreibung

The CD24 antigen, which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002).
CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002).

Spezifität

Antibody recognizes Human CD24 antigen.

Immunogen

Isolated membrane fraction of the pre-B leukemic cell line NALM-1.

Anwendung

Research Category
Entzündung & Immunologie

Research Sub Category
Immunoglobuline & Immunologie

Detect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC.

Qualität

Evaluated by flow cytometry using human PBMCs

Zielbeschreibung

35-45 kDa (Turni, 2002)

Physikalische Form

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Lagerung und Haltbarkeit

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Hinweis zur Analyse

Control
PBMCs

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Rechtliche Hinweise

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable