EZHFGF23

Human FGF-23 ELISA Kit

measuress and quantifies FGF-23 levels in 50 μL serum, plasma or cell culture supernatent

• Synonym(e): ELISA Kit for Human FGF-23, FGF-23 ELISA, Human FGF-23 Detection
• UNSPSC-Code: 12161503
• eCl@ss: 32161000
• NACRES: NA.32

Eigenschaften

• product name: Human FGF-23 ELISA Kit, This Human FGF-23 ELISA Kit is used to measure & quantify FGF-23 levels in Metabolism & Inflammation & Immunology research.
• Qualitätsniveau: 200
• Speziesreaktivität: human
• Verpackung: kit of 1 × 96 wells
• Parameter: 50 μL sample volume (4hr assay)
• assay range: sensitivity: 9.9 pg/mL; (minimum detectable concentrations in tissue culture/serum/plasma); standard curve range: 9.9-2400 pg/mL; inter-assay cv: <11%; intra-assay cv: <11%
• Methode(n): ELISA: suitable
• Aufnahme: sample type cell culture supernatant; sample type serum; sample type plasma (K2 EDTA)
• Anwendung(en): research use
• Nachweisverfahren: colorimetric (450nm/590nm)
• Versandbedingung: wet ice
• Lagertemp.: 2-8°C

Beschreibung

Allgemeine Beschreibung

Studies demonstrate that Fibroblast Growth Hormone-23 plays a critical role as a phosphate-regulating hormone. FGF-23 is responsible for the inhibition of renal tubular reabsorption of inorganic phosphorus and, consequently, the regulation of phosphorus homeostasis. FGF-23 mRNA is expressed in the brain, in the thymus at low levels, in dendritic cells, with the highest expression in osteocytes and osteoblasts during phases of active bone remodeling. Because circulating levels of FGF-23 are regulated by vitamin D and phosphorus, normal skeletal and soft tissue development require vitamin D and a functional vitamin D signaling pathway. Diseases resulting from aberrant FGF-23 expression include inherited forms of rickets, certain kidney diseases and phosphorus-related tumors.

Spezifität

The antibody pair used in this assay cross-reacts 0.01% to Human FGF- 21 and 0.01% to FGF-19.

No significant cross-reactivity has been observed to other human and rat molecules/hormones tested

Anwendung

Research Category
Stammzellforschung

50µl sample size, 2-Step assay with <4hr incubation time.

Used to detect/quantify: FGF-23

Sonstige Hinweise

Please contact Technical Service for linearity of dilution.

Haftungsausschluss

For research use only. Not for use in diagnostic procedures.

Sicherheitshinweise

• Piktogramme: GHS06,GHS05,GHS09
• Signalwort: Danger
• H-Sätze: H290,H302 + H332,H311,H317,H411
• P-Sätze: P234 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312
• Gefahreneinstufungen: Acute Tox. 3 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral - Aquatic Chronic 2 - Met. Corr. 1 - Skin Sens. 1
• Lagerklassenschlüssel: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects