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Merck

AQ502P

Sigma-Aldrich

Goat Anti-Mouse IgM+IgG+IgA Antibody, F(ab′)2, HRP conjugate, Species Adsorbed

Chemicon®, from goat

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.46

Biologische Quelle

goat

Qualitätsniveau

Konjugat

peroxidase conjugate

Antikörperform

purified antibody

Antikörper-Produkttyp

secondary antibodies

Klon

polyclonal

Speziesreaktivität

mouse

Hersteller/Markenname

Chemicon®

Methode(n)

ELISA: suitable

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Allgemeine Beschreibung

IgG is the most abundant immunoglobulin and comprises two heavy chains and two light chains. Each molecule has two antigen binding sites. IgG has 4 subclasses: IgG1 (66%), IgG2 (23%), IgG3 (7%) and IgG4 (4%). IgM constitutes about 10% of serum immunoglobulins. IgM (with IgD) is the major immunoglobulin expressed on the surface of B cells. Monomeric IgA constitutes 5-15 % of the serum immunoglobulins whereas dimeric IgA is localized to mucosa surfaces.

Spezifität

Reacts with heavy and light chains of mouse IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA. Absorbed for human sera and purified human paraproteins. Minimal cross reactivity with human immunoglobulins.
The antibody reacts with the heavy and light chains of mouse IgM, IgG1, IgG2a, IgG2b, IgG3 and IgA as demonstrated by ELISA and flow cytometry. Minimal cross reactivity with human immunoglobulins.

Immunogen

Epitope: Mouse IgM, IgG, IgA
Prepared from pepsin digest of mouse Ig (H+L).

Anwendung

Research Category
Sekundär- & Kontrollantikörper
Research Sub Category
Fragmentspezifische Sekundärantikörper
ELISA: 1:4,000-1:8,000.

Optimal working dilutions must be determined by the end user.
This Goat anti-Mouse IgM+IgG+IgA Antibody, F(ab′)2, HRP conjugate, Species Adsorbed is validated for use in ELISA for the detection of Mouse IgM+IgG+IgA.

Physikalische Form

Gel filtration chromatography
Purified by gel filtration chromatography of pepsin digested antibody. Liquid in 50% glycerol/50% PBS, pH 7.4.

Lagerung und Haltbarkeit

Maintain refrigerated at 2°-8°C under sterile conditions for up to twelve months from date of receipt. For long term storage, aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 2


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John E La Marca et al.
International journal of molecular sciences, 22(23) (2021-12-11)
Tissue homeostasis via the elimination of aberrant cells is fundamental for organism survival. Cell competition is a key homeostatic mechanism, contributing to the recognition and elimination of aberrant cells, preventing their malignant progression and the development of tumors. Here, using

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