ABN38

Anti-RAB35 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Ras-related protein Rab-35, GTP-binding protein RAY, Ras-related protein Rab-1C
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: rat, human, horse
• Speziesreaktivität (Voraussage durch Homologie): canine (based on 100% sequence homology), equine (based on 100% sequence homology)
• Methode(n): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI-Hinterlegungsnummer: NP_006852
• UniProt-Hinterlegungsnummer: Q15286
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... RAB35(11021)

Beschreibung

Allgemeine Beschreibung

RAB35 is a member of the Rab GTPases identified in the human genome. It is ubiquitously expressed and regulates a fast endocytotic recycling events associated with the terminal steps of cytokinesis, the formation of immunological synapse, and peptide loading onto major histocompatibility complex III molecules. RAB35 also plays a significant role in the formation of the immunological synapse (IS) between peptide-loaded antigen presenting cells (APCs) and T cells.

Spezifität

This antibody recognizes RAB35 at the C-terminus.

Immunogen

KLH-conjugated linear peptide corresponding to the C-terminus of human RAB35.

Anwendung

Immunohistochemistry Analysis: A 1:500 dilution from a representative lot detected RAB35 in normal human brain tissue.

This Anti-RAB35 Antibody is validated for use in WB, IH(P) for the detection of RAB35.

Qualität

Evaluated by Western Blot in human brain tissue lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected RAB35 on 10 µg of human brain tissue lysate.

Zielbeschreibung

~19 kDa observed. The calculated molecular weight is 23 kDa

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable