ABN254

Anti-BAALC Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Brain and acute leukemia cytoplasmic protein, BAALC
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: rat, mouse
• Speziesreaktivität (Voraussage durch Homologie): human (based on 100% sequence homology), bovine (based on 100% sequence homology), porcine (based on 100% sequence homology)
• Methode(n): western blot: suitable
• NCBI-Hinterlegungsnummer: NP_079088
• UniProt-Hinterlegungsnummer: Q8WXS3
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... BAALC(79870)

Beschreibung

Allgemeine Beschreibung

Brain and acute leukemia cytoplasmic protein (BAALC) interacts with CAMK2A in a synaptic role at postsynaptic lipid rafts. BAALC is expressed by neural, hematopoietic, normal early progenitor cells and in the most immature type of blasts in acute leukemia. Isoform 2 and isoform 6 are also expressed in the brain.

Spezifität

This antibody recognizes the CAMK2A interaction domain of BAALC. This antibody should recognize all isoforms in uniprot.

Immunogen

Epitope: CAMK2A interaction domain

KLH-conjugated linear peptide corresponding to the CAMK2A interaction domain of human BAALC.

Anwendung

Research Category
Neurowissenschaft

Research Sub Category
Entwicklungsabhängige Signalübertragung

Detect Brain & acute leukemia cytoplasmic protein using this rabbit polyclonal antibody, Anti-BAALC Antibody validated for use in western blotting.

Qualität

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected BAALC in 10 µg of mouse brain tissue lysate.

Zielbeschreibung

~22 kDa observed. Uniprot describes 6 isoforms produced by alternative splicing at ~19 kDa, ~16 kDa, ~9 kDa, ~8 kDa and ~6 kDa

Physikalische Form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Mouse brain tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable