ABN207

Anti-DBN1 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Drebrin, Developmentally-regulated brain protein, DBN1
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: mouse, horse, human, rat
• Speziesreaktivität (Voraussage durch Homologie): bovine (based on 100% sequence homology), equine (based on 100% sequence homology)
• Methode(n): immunohistochemistry: suitable (paraffin); western blot: suitable
• NCBI-Hinterlegungsnummer: NP_004386
• UniProt-Hinterlegungsnummer: Q16643
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... DBN1(1627)

Beschreibung

Allgemeine Beschreibung

Drebrin (Developmentally-regulated brain protein) is also known by the gene name DBN1. Drebrins are found in the cytoplasm of brain neurons as well as tissues including heart, placenta skeletal muscle kidney and pancreas. Debrin binds F-actin and is involved in the mechanisms of development, cell migration, neuronal processes and dendrite plasticity.

Immunogen

KLH-conjugated linear peptide corresponding to human DBN1.

Anwendung

Research Category
Neurowissenschaft

Research Sub Category
Entwicklungsabhängige Signalübertragung

Immunohistochemistry Analysis: A 1:4,000 dilution from a representative lot detected DBN1 in human cerebellum and rat midbrain tissues.

This DBN1 antibody is validated for use in WB & IHC for the detection of the DBN1 protein.

Qualität

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 0.25 µg/mL of this antibody detected DBN1 in 10 µg of mouse brain tissue lysate.

Zielbeschreibung

~110 kDa observed. The calculated molecular weight is 71 kDa, however DBN1 has been shown as a ~110 kDa band in western blotting (Maezawa, I., et al. (2006). Novus Biologicals. 1-2).

Verlinkung

Replaces: AB15288

Physikalische Form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Mouse brain tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable