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Key Documents

ABE600

Sigma-Aldrich

Anti-SATB2 Antibody

from rabbit, purified by affinity chromatography

Synonym(e):

DNA-binding protein SATB2, Special AT-rich sequence-binding protein 2

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity isolated antibody

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

human, mouse

Methode(n)

immunofluorescence: suitable
immunohistochemistry: suitable (paraffin)
western blot: suitable

UniProt-Hinterlegungsnummer

Versandbedingung

wet ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... SATB2(23314)

Allgemeine Beschreibung

Special AT-rich sequence-binding protein 2 (SATB2) contains 2 CUT DNA-binding domains and one homeobox DNA binding domain belonging to the CUT homeobox family. SATB2 binds to DNA at the nuclear matri or scaffold-associated regions. SATB2 is highly expressed in adult brain, moderately expressed in fetal brain, and weakly expressed in adult liver, kidney, and spinal cord. Mutations in SATB2 have been associated with cleft palate.

Spezifität

This antibody recognizes the N-terminus of SATB2.

Immunogen

Epitope: N-terminus
KLH-conjugated linear peptide corresponding to the N-terminus of human SATB2.

Anwendung

Research Category
Epigenetik & nukleäre Funktionen
Research Sub Category
Transkriptionsfaktoren
Detect Special AT-rich sequence-binding protein 2 using this rabbit polyclonal antibody, Anti-SATB2 Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.
Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected SATB2 in human brain tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected SATB2 in human brain cells.

Qualität

Evaluated by Western Blotting in mouse brain tissue lysate.

Western Blotting Analysis: 4 µg/mL of this antibody detected SATB2 in 15 µg of mouse brain tissue lysate.

Zielbeschreibung

~90 kDa observed

Physikalische Form

Antigen Affinity Purified
Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Mouse brain tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

12 - Non Combustible Liquids

WGK

WGK 2

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Lei Wang et al.
Nature neuroscience, 19(7), 888-896 (2016-05-24)
The unique mental abilities of humans are rooted in the immensely expanded and folded neocortex, which reflects the expansion of neural progenitors, especially basal progenitors including basal radial glia (bRGs) and intermediate progenitor cells (IPCs). We found that constitutively active

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