ABD134

Anti-BMP Antibody15

from rabbit, purified by affinity chromatography

• Synonym(e): Bone morphogenetic protein 15, BMP-15, Growth/differentiation factor 9B, GDF9B, GDF-9B, ODG2, POF4
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: mouse
• Speziesreaktivität (Voraussage durch Homologie): human (immunogen homology)
• Methode(n): immunocytochemistry: suitable; western blot: suitable
• UniProt-Hinterlegungsnummer: O95972
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... BMP15(9210) ; mouse ... Bmp15(12155)

Beschreibung

Allgemeine Beschreibung

Bone morphogenetic protein 15 (BMP15), also known as Growth/differentiation factor 9B (GDF9B), is part of the transforming growth factor-beta (TGF-β) superfamily. BMP15 is an oocyte-specific growth and differentiation factor that stimulates folliculogenesis and development as well as granulosa cell (GC) growth. BMP15 is expressed exclusively in the oocyte. BMP15 defects are linked to ovarian dysgenesis type 2 (ODG2) and premature ovarian failure type 4 (POF4). Potentially, BMP15 could be an oogenesis marker, used to monitor the differentiation of human amniotic fluid stem cells into oocyte-like cells.

Immunogen

KLH-conjugated linear peptide corresponding to human BMP15.

Anwendung

Research Category
Stammzellforschung

Research Sub Category
Pluripotente Stammzellen & Stammzellen der frühen Entwicklungsphase

Anti-BMP Antibody15 is a highly specific rabbit polyclonal antibody, that targets BMP & has been tested in western blotting & ICC.

Immunocytochemistry Analysis: 2.5 µg/mL from a representative lot detected BMP15 in NIH/3T3 cells.

Qualität

Evaluated by Western Blotting in NIH/3T3 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected BMP15 in 15 µg of NIH/3T3 cell lysate.

Zielbeschreibung

~53 kDa observed. Uncharacterized bands may appear in some lysate(s).

Physikalische Form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
NIH/3T3 cell lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable