ABC430

Anti-FABP1 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, p14
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: rat, human
• Speziesreaktivität (Voraussage durch Homologie): primate (based on 100% sequence homology)
• Methode(n): immunohistochemistry: suitable; western blot: suitable
• NCBI-Hinterlegungsnummer: NP_001434
• UniProt-Hinterlegungsnummer: P07148
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... FABP1(2168)

Beschreibung

Allgemeine Beschreibung

FABP1, also known as Fatty acid-binding protein, Liver Fatty acid-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, or p14, and encoded by the gene FABP1/FABPL, is an important fatty acid binding and transport protein. FABP1 is produced in the liver and is part of a family of lipid carrier proteins. FABP1 facilitate the transfer of fatty acids between extra and intracellular membranes. FABP1 level in the blood is used as a biomarker for obesity and type II diabetes. Additionally, recent research indicates that FABP1 can modulate stellate cell activation and this may lead to diet-induced nonalcoholic fatty liver disease, thus FABP1 is a key focus of metabolic research.

Spezifität

Other homologies: Mouse (94% sequence homology).

Immunogen

Epitope: Near N-terminus

KLH-conjugated linear peptide corresponding to human FABP1 near the N-terminus.

Anwendung

Research Category
Apoptose & Krebs

Research Sub Category
Apoptose - Weiterführende Produkte

Immunohistochemistry Analysis: A 1:2,000 dilution from a representative lot detected FABP1 in rat liver tissue.

This Anti-FABP1 Antibody is validated for use in Western Blotting and Immunohistochemistry for the detection of FABP1.

Qualität

Evaluated by Western Blotting in HepG2 cell lysate.

Western Blotting Analysis: 2.0 µg/mL of this antibody detected FABP1 in 10 µg of HepG2 cell lysate.

Zielbeschreibung

~14 kDa observed

Physikalische Form

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Sonstige Hinweise

Concentration: Please refer to lot specific datasheet.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable