AB9870
Anti-STIM1 Antibody
Chemicon®, from rabbit
Synonym(e):
Stromal interaction molecule 1
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About This Item
UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Empfohlene Produkte
Biologische Quelle
rabbit
Qualitätsniveau
Antikörperform
purified antibody
Antikörper-Produkttyp
primary antibodies
Klon
polyclonal
Speziesreaktivität
human, mouse
Hersteller/Markenname
Chemicon®
Methode(n)
western blot: suitable
UniProt-Hinterlegungsnummer
Versandbedingung
wet ice
Posttranslationale Modifikation Target
unmodified
Angaben zum Gen
human ... CAV1(857) , NUP98(4928) , ORAI1(84876)
Allgemeine Beschreibung
TRP (transient receptor potential)-related ion channels (TRPCs) have been postulated as candidates for forming both receptor-operated (ROCE) and capacitative Ca2+ entry channels across the plasma membrane. ER transmembrane protein STIM1 senses the depletion of Ca2+ from ER stores. Orai proteins, interacting with TRPCs, act as regulatory subunits that confers STIM1-mediated store depletion sensitivity to these channels and regulate Ca2+ influx through the plasma membrane.
Spezifität
Catalogue No. AB9870 recognizes the C-Terminus of STIM1.
Immunogen
Synthetic Linear Peptide
Anwendung
Research Category
Neurowissenschaft
Neurowissenschaft
Research Sub Category
Ionenkanäle & -transporter
Ionenkanäle & -transporter
Anti-STIM1 Antibody is an antibody against STIM1 for use in WB.
Optimal working dilutions must be determined by the end user.
Qualität
Routinely evaluated in western blotting using Jurkat lysate.
Zielbeschreibung
80 kDa
Physikalische Form
Protein A purified
Format: Purified
Purified in PBS with 0.05% NaN3
Lagerung und Haltbarkeit
Maintain at 2-8°C in undiluted aliquots for up to 1 year after date of receipt.
Hinweis zur Analyse
Control
Jurkat lysate.
Jurkat lysate.
Rechtliche Hinweise
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Haftungsausschluss
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Lagerklassenschlüssel
10 - Combustible liquids
WGK
WGK 2
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Analysenzertifikate (COA)
Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.
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Journal of cell science, 130(18), 3083-3093 (2017-08-02)
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Background: Spectrin, beta, non-erythrocytic 1 (SPTBN1), an adapter protein for transforming growth factor beta (TGF-β) signaling, is recognized as a tumor suppressor in the development of hepatocellular carcinoma (HCC); however, the underlying molecular mechanisms of this tumor suppression remain obscure.
Agnieszka Dyrda et al.
Cell calcium, 86, 102134-102134 (2019-12-16)
During myogenesis, a long splice variant of STIM1, called STIM1L is getting expressed, while the level of STIM1 remains constant. Previous work demonstrated that STIM1L is more efficient in eliciting store-operated Ca2+ entry (SOCE), but no current analysis of the
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