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Key Documents

AB5986P

Sigma-Aldrich

Anti-Tyrosine Hydroxylase Antibody

Chemicon®, from rabbit

Synonym(e):

TH, Tyrosine Monooxygenase

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

rabbit

Qualitätsniveau

Antikörperform

affinity purified immunoglobulin

Antikörper-Produkttyp

primary antibodies

Klon

polyclonal

Aufgereinigt durch

affinity chromatography

Speziesreaktivität

rat

Hersteller/Markenname

Chemicon®

Methode(n)

immunohistochemistry: suitable

NCBI-Hinterlegungsnummer

UniProt-Hinterlegungsnummer

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Angaben zum Gen

human ... TH(7054)

Spezifität

Tyrosine Hydroxylase. Immunohistochemical distribution throughout the brain shows that staining is restricted to those neurons known to contain the enzyme. The antibody has proven useful in staining catecholaminergic neurons. AB5986 stains these neurons intensely, including dendritic processes and fine nerve terminals.

Immunogen

Synthetic peptide corresponding to amino acids 32-47 of rat Tyrosine Hydroxylase.

Anwendung

Research Category
Neurowissenschaft
Research Sub Category
Neurotransmitter & Rezeptoren

Neuronen- & Gliamarker
Detect Tyrosine Hydroxylase using this Anti-Tyrosine Hydroxylase Antibody validated for use in IH.
Immunohistochemistry: 0.5-1.0 μg/mL.

Optimal working dilutions must be determined by end user.

Physikalische Form

Affinity purified immunoglobulin.

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable


Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

D Rotllant et al.
Neuroscience, 168(3), 691-705 (2010-04-22)
Previous studies have shown that amphetamine (AMPH) markedly activates dopaminergic projection areas, together with some important limbic nuclei. However, a global picture of the brain areas activated is lacking and the contribution of the dose of the drug and individual
Immunohistochemical studies on phosphorylation of tyrosine hydroxylase in central catecholamine neurons using site- and phosphorylation state-specific antibodies.
Xu, Z Q, et al.
Neuroscience, 82, 727-738 (1998)
Stephanie J Cragg et al.
The European journal of neuroscience, 20(7), 1788-1802 (2004-09-24)
The direct modulation of subthalamic nucleus (STN) neurons by dopamine (DA) neurons of the substantia nigra (SN) is controversial owing to the thick caliber and low density of DA axons in the STN. The abnormal activity of the STN in
Antibodies to a segment of tyrosine hydroxylase phosphorylated at serine 40.
Goldstein, M, et al.
Journal of Neurochemistry, 64, 2281-2287 (1995)
Antibodies to a synthetic peptide corresponding to a Ser-40-containing segment of tyrosine hydroxylase: activation and immunohistochemical localization of tyrosine hydroxylase.
Lee, K Y, et al.
Journal of Neurochemistry, 53, 1238-1244 (1989)

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